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Aluminium Phosphide Poisoning: Early Suspicion of Cardiotoxicity Is Necessary for Improved Outcomes

Poisoning is one of the more conventional modes of suicide in some parts of India. Aluminium phosphide (ALP) is a chemical used for this purpose and manifests severe cardiovascular complications, such as hypotension, shock, various arrhythmias, congestive heart failure with toxic myocarditis, and in...

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Detalles Bibliográficos
Autores principales: Sahoo, Debananda, Kujur, Shiny T, Das, Dhriti Sundar, Dey, Anupam, Devi, Sujata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535943/
https://www.ncbi.nlm.nih.gov/pubmed/33042678
http://dx.doi.org/10.7759/cureus.10237
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author Sahoo, Debananda
Kujur, Shiny T
Das, Dhriti Sundar
Dey, Anupam
Devi, Sujata
author_facet Sahoo, Debananda
Kujur, Shiny T
Das, Dhriti Sundar
Dey, Anupam
Devi, Sujata
author_sort Sahoo, Debananda
collection PubMed
description Poisoning is one of the more conventional modes of suicide in some parts of India. Aluminium phosphide (ALP) is a chemical used for this purpose and manifests severe cardiovascular complications, such as hypotension, shock, various arrhythmias, congestive heart failure with toxic myocarditis, and in rare cases, ST-segment elevation myocardial infarction or other electrocardiogram changes. Upon contact with moisture, ALP yields phosphine gas, a toxic systemic poison found in pesticides that can lead to cardiovascular-related mortality. We present a case of ALP poisoning in a 60-year-old woman who was asymptomatic for the first 48 hours. She gradually developed cardiac complications in the form of anteroseptal acute myocardial infarction (AMI). As AMI is very rare among the various cardiac complications, an early vigilance is necessary to prevent further complications in ALP poisoning.
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spelling pubmed-75359432020-10-08 Aluminium Phosphide Poisoning: Early Suspicion of Cardiotoxicity Is Necessary for Improved Outcomes Sahoo, Debananda Kujur, Shiny T Das, Dhriti Sundar Dey, Anupam Devi, Sujata Cureus Cardiology Poisoning is one of the more conventional modes of suicide in some parts of India. Aluminium phosphide (ALP) is a chemical used for this purpose and manifests severe cardiovascular complications, such as hypotension, shock, various arrhythmias, congestive heart failure with toxic myocarditis, and in rare cases, ST-segment elevation myocardial infarction or other electrocardiogram changes. Upon contact with moisture, ALP yields phosphine gas, a toxic systemic poison found in pesticides that can lead to cardiovascular-related mortality. We present a case of ALP poisoning in a 60-year-old woman who was asymptomatic for the first 48 hours. She gradually developed cardiac complications in the form of anteroseptal acute myocardial infarction (AMI). As AMI is very rare among the various cardiac complications, an early vigilance is necessary to prevent further complications in ALP poisoning. Cureus 2020-09-04 /pmc/articles/PMC7535943/ /pubmed/33042678 http://dx.doi.org/10.7759/cureus.10237 Text en Copyright © 2020, Sahoo et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Sahoo, Debananda
Kujur, Shiny T
Das, Dhriti Sundar
Dey, Anupam
Devi, Sujata
Aluminium Phosphide Poisoning: Early Suspicion of Cardiotoxicity Is Necessary for Improved Outcomes
title Aluminium Phosphide Poisoning: Early Suspicion of Cardiotoxicity Is Necessary for Improved Outcomes
title_full Aluminium Phosphide Poisoning: Early Suspicion of Cardiotoxicity Is Necessary for Improved Outcomes
title_fullStr Aluminium Phosphide Poisoning: Early Suspicion of Cardiotoxicity Is Necessary for Improved Outcomes
title_full_unstemmed Aluminium Phosphide Poisoning: Early Suspicion of Cardiotoxicity Is Necessary for Improved Outcomes
title_short Aluminium Phosphide Poisoning: Early Suspicion of Cardiotoxicity Is Necessary for Improved Outcomes
title_sort aluminium phosphide poisoning: early suspicion of cardiotoxicity is necessary for improved outcomes
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535943/
https://www.ncbi.nlm.nih.gov/pubmed/33042678
http://dx.doi.org/10.7759/cureus.10237
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