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TAK1: a potent tumour necrosis factor inhibitor for the treatment of inflammatory diseases

Aberrant tumour necrosis factor (TNF) signalling is a hallmark of many inflammatory diseases including rheumatoid arthritis (RA), irritable bowel disease and lupus. Maladaptive TNF signalling can lead to hyper active downstream nuclear factor (NF)-κβ signalling in turn amplifying a cell's infla...

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Detalles Bibliográficos
Autores principales: Totzke, Juliane, Scarneo, Scott A., Yang, Kelly W., Haystead, Timothy A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536066/
https://www.ncbi.nlm.nih.gov/pubmed/32873150
http://dx.doi.org/10.1098/rsob.200099