SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals

SARS-CoV-2 has a zoonotic origin and was transmitted to humans via an undetermined intermediate host, leading to infections in humans and other mammals. To enter host cells, the viral spike protein (S-protein) binds to its receptor, ACE2, and is then processed by TMPRSS2. Whilst receptor binding con...

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Detalles Bibliográficos
Autores principales: Lam, S. D., Bordin, N., Waman, V. P., Scholes, H. M., Ashford, P., Sen, N., van Dorp, L., Rauer, C., Dawson, N. L., Pang, C. S. M., Abbasian, M., Sillitoe, I., Edwards, S. J. L., Fraternali, F., Lees, J. G., Santini, J. M., Orengo, C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536205/
https://www.ncbi.nlm.nih.gov/pubmed/33020502
http://dx.doi.org/10.1038/s41598-020-71936-5

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