Cargando…
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage
To perform their computational function, genetic circuits change states through a symphony of genetic parts that turn regulator expression on and off. Debugging is frustrated by an inability to characterize parts in the context of the circuit and identify the origins of failures. Here, we take snaps...
Autores principales: | Espah Borujeni, Amin, Zhang, Jing, Doosthosseini, Hamid, Nielsen, Alec A. K., Voigt, Christopher A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536230/ https://www.ncbi.nlm.nih.gov/pubmed/33020480 http://dx.doi.org/10.1038/s41467-020-18630-2 |
Ejemplares similares
-
Genetic circuit characterization and debugging using RNA‐seq
por: Gorochowski, Thomas E, et al.
Publicado: (2017) -
Precision design of stable genetic circuits carried in highly‐insulated E. coli genomic landing pads
por: Park, Yongjin, et al.
Publicado: (2020) -
Dynamic control of endogenous metabolism with combinatorial logic circuits
por: Moser, Felix, et al.
Publicado: (2018) -
Precise quantification of translation inhibition by mRNA structures that overlap with the ribosomal footprint in N-terminal coding sequences
por: Espah Borujeni, Amin, et al.
Publicado: (2017) -
Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites
por: Espah Borujeni, Amin, et al.
Publicado: (2014)