Isodeoxyelephantopin Inactivates Thioredoxin Reductase 1 and Activates ROS-Mediated JNK Signaling Pathway to Exacerbate Cisplatin Effectiveness in Human Colon Cancer Cells

Colon cancer is one of the leading causes of cancer-related death in the world. The development of new drugs and therapeutic strategies for patients with colon cancer are urgently needed. Isodeoxyelephantopin (ESI), a sesquiterpene lactone isolated from the medicinal plant Elephantopus scaber L., ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Lin, Chen, Jundixia, Wu, Fang, Wu, Fengjiao, Shen, Xin, Zheng, Peisen, Shao, Rongrong, Lu, Kongqin, Liu, Zhiguo, Chen, Daoxing, Liang, Guang, Cai, Yuepiao, Zou, Peng, Xia, Yiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536313/
https://www.ncbi.nlm.nih.gov/pubmed/33072762
http://dx.doi.org/10.3389/fcell.2020.580517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536313/
https://www.ncbi.nlm.nih.gov/pubmed/33072762
http://dx.doi.org/10.3389/fcell.2020.580517

Ejemplares similares