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Geriatric Population During the COVID-19 Pandemic: Problems, Considerations, Exigencies, and Beyond
The coronavirus disease 2019 (COVID-19) pandemic wreaked havoc worldwide, with more than 20 million confirmed cases and nearly 0. 75 million deaths as of 10th August 2020. Various factors determine the severity and symptoms of this infection. Older age and underlying diseases are the challenges bein...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536316/ https://www.ncbi.nlm.nih.gov/pubmed/33072713 http://dx.doi.org/10.3389/fpubh.2020.574198 |
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author | Dhama, Kuldeep Patel, Shailesh Kumar Kumar, Rakesh Rana, Jigyasa Yatoo, Mohd. Iqbal Kumar, Akshay Tiwari, Ruchi Dhama, Jaideep Natesan, Senthilkumar Singh, Rajendra Harapan, Harapan |
author_facet | Dhama, Kuldeep Patel, Shailesh Kumar Kumar, Rakesh Rana, Jigyasa Yatoo, Mohd. Iqbal Kumar, Akshay Tiwari, Ruchi Dhama, Jaideep Natesan, Senthilkumar Singh, Rajendra Harapan, Harapan |
author_sort | Dhama, Kuldeep |
collection | PubMed |
description | The coronavirus disease 2019 (COVID-19) pandemic wreaked havoc worldwide, with more than 20 million confirmed cases and nearly 0. 75 million deaths as of 10th August 2020. Various factors determine the severity and symptoms of this infection. Older age and underlying diseases are the challenges being faced in controlling and treating COVID-19. In 2019, 703 million of the global population was older than 65 years of age. The estimated mortality due to COVID-19 in people older than 76 years of age is reportedly 18%. Frequent infections in older people, higher disease severity, and increased mortality are major challenges in the implementation of appropriate preventive measures and future strategies to protect against this disease in geriatric population. Poor health status, weak immune function, lowered organ function, increased probability of multiple underlying diseases, and poor attention to personal health can increase the susceptibility to various diseases in the geriatric population. Concerning inadequate immunity, the decrease expression of receptors and exaggerated pathophysiologic responses can be debilitating. However, future studies will reveal the hidden facets in these aspects in this COVID-19 catastrophe. In this article, we reviewed the main concerns of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the geriatric population, including the risk of acquiring severe COVID-19 resulting in mortality, variation in clinical manifestations, and other pandemic-related concerns. We also discussed the need for increasing attention toward the elderly, taking appropriate prevention and control measures, and considering geriatric-related adjustments in vaccine design and development. |
format | Online Article Text |
id | pubmed-7536316 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-75363162020-10-16 Geriatric Population During the COVID-19 Pandemic: Problems, Considerations, Exigencies, and Beyond Dhama, Kuldeep Patel, Shailesh Kumar Kumar, Rakesh Rana, Jigyasa Yatoo, Mohd. Iqbal Kumar, Akshay Tiwari, Ruchi Dhama, Jaideep Natesan, Senthilkumar Singh, Rajendra Harapan, Harapan Front Public Health Public Health The coronavirus disease 2019 (COVID-19) pandemic wreaked havoc worldwide, with more than 20 million confirmed cases and nearly 0. 75 million deaths as of 10th August 2020. Various factors determine the severity and symptoms of this infection. Older age and underlying diseases are the challenges being faced in controlling and treating COVID-19. In 2019, 703 million of the global population was older than 65 years of age. The estimated mortality due to COVID-19 in people older than 76 years of age is reportedly 18%. Frequent infections in older people, higher disease severity, and increased mortality are major challenges in the implementation of appropriate preventive measures and future strategies to protect against this disease in geriatric population. Poor health status, weak immune function, lowered organ function, increased probability of multiple underlying diseases, and poor attention to personal health can increase the susceptibility to various diseases in the geriatric population. Concerning inadequate immunity, the decrease expression of receptors and exaggerated pathophysiologic responses can be debilitating. However, future studies will reveal the hidden facets in these aspects in this COVID-19 catastrophe. In this article, we reviewed the main concerns of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the geriatric population, including the risk of acquiring severe COVID-19 resulting in mortality, variation in clinical manifestations, and other pandemic-related concerns. We also discussed the need for increasing attention toward the elderly, taking appropriate prevention and control measures, and considering geriatric-related adjustments in vaccine design and development. Frontiers Media S.A. 2020-09-22 /pmc/articles/PMC7536316/ /pubmed/33072713 http://dx.doi.org/10.3389/fpubh.2020.574198 Text en Copyright © 2020 Dhama, Patel, Kumar, Rana, Yatoo, Kumar, Tiwari, Dhama, Natesan, Singh and Harapan. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Dhama, Kuldeep Patel, Shailesh Kumar Kumar, Rakesh Rana, Jigyasa Yatoo, Mohd. Iqbal Kumar, Akshay Tiwari, Ruchi Dhama, Jaideep Natesan, Senthilkumar Singh, Rajendra Harapan, Harapan Geriatric Population During the COVID-19 Pandemic: Problems, Considerations, Exigencies, and Beyond |
title | Geriatric Population During the COVID-19 Pandemic: Problems, Considerations, Exigencies, and Beyond |
title_full | Geriatric Population During the COVID-19 Pandemic: Problems, Considerations, Exigencies, and Beyond |
title_fullStr | Geriatric Population During the COVID-19 Pandemic: Problems, Considerations, Exigencies, and Beyond |
title_full_unstemmed | Geriatric Population During the COVID-19 Pandemic: Problems, Considerations, Exigencies, and Beyond |
title_short | Geriatric Population During the COVID-19 Pandemic: Problems, Considerations, Exigencies, and Beyond |
title_sort | geriatric population during the covid-19 pandemic: problems, considerations, exigencies, and beyond |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536316/ https://www.ncbi.nlm.nih.gov/pubmed/33072713 http://dx.doi.org/10.3389/fpubh.2020.574198 |
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