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Caenorhabditis elegans SET1/COMPASS Maintains Germline Identity by Preventing Transcriptional Deregulation Across Generations

Chromatin regulators contribute to the maintenance of the germline transcriptional program. In the absence of SET-2, the Caenorhabditis elegans homolog of the SET1/COMPASS H3 Lys4 (H3K4) methyltransferase, animals show transgenerational loss of germline identity, leading to sterility. To identify tr...

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Detalles Bibliográficos
Autores principales: Robert, Valérie J., Knutson, Andrew K., Rechtsteiner, Andreas, Garvis, Steven, Yvert, Gaël, Strome, Susan, Palladino, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536326/
https://www.ncbi.nlm.nih.gov/pubmed/33072747
http://dx.doi.org/10.3389/fcell.2020.561791