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The CHIR Score for Evaluating the Hyperimmune Response in COVID-19: A Preliminary Concept

Similar to SARS and MERS, the host immune response to COVID-19 is implicated in the severity of the disease itself. Here, we investigate the possible use of scoring systems to help guide clinicians in their determination as to when to commence immunosuppressive treatment in COVID-19. We utilized the...

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Detalles Bibliográficos
Autores principales: Goyal, Daniel Kumar, Mansab, Fatma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536342/
https://www.ncbi.nlm.nih.gov/pubmed/33072695
http://dx.doi.org/10.3389/fpubh.2020.550933
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author Goyal, Daniel Kumar
Mansab, Fatma
author_facet Goyal, Daniel Kumar
Mansab, Fatma
author_sort Goyal, Daniel Kumar
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description Similar to SARS and MERS, the host immune response to COVID-19 is implicated in the severity of the disease itself. Here, we investigate the possible use of scoring systems to help guide clinicians in their determination as to when to commence immunosuppressive treatment in COVID-19. We utilized the relatively established clinical and biochemical severity indicators from large cohort studies to develop a potential scoring system for the hyperimmune response in COVID-19.
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spelling pubmed-75363422020-10-16 The CHIR Score for Evaluating the Hyperimmune Response in COVID-19: A Preliminary Concept Goyal, Daniel Kumar Mansab, Fatma Front Public Health Public Health Similar to SARS and MERS, the host immune response to COVID-19 is implicated in the severity of the disease itself. Here, we investigate the possible use of scoring systems to help guide clinicians in their determination as to when to commence immunosuppressive treatment in COVID-19. We utilized the relatively established clinical and biochemical severity indicators from large cohort studies to develop a potential scoring system for the hyperimmune response in COVID-19. Frontiers Media S.A. 2020-09-22 /pmc/articles/PMC7536342/ /pubmed/33072695 http://dx.doi.org/10.3389/fpubh.2020.550933 Text en Copyright © 2020 Goyal and Mansab. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Goyal, Daniel Kumar
Mansab, Fatma
The CHIR Score for Evaluating the Hyperimmune Response in COVID-19: A Preliminary Concept
title The CHIR Score for Evaluating the Hyperimmune Response in COVID-19: A Preliminary Concept
title_full The CHIR Score for Evaluating the Hyperimmune Response in COVID-19: A Preliminary Concept
title_fullStr The CHIR Score for Evaluating the Hyperimmune Response in COVID-19: A Preliminary Concept
title_full_unstemmed The CHIR Score for Evaluating the Hyperimmune Response in COVID-19: A Preliminary Concept
title_short The CHIR Score for Evaluating the Hyperimmune Response in COVID-19: A Preliminary Concept
title_sort chir score for evaluating the hyperimmune response in covid-19: a preliminary concept
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536342/
https://www.ncbi.nlm.nih.gov/pubmed/33072695
http://dx.doi.org/10.3389/fpubh.2020.550933
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