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Generation and trapping of a mesoderm biased state of human pluripotency

We postulate that exit from pluripotency involves intermediates that retain pluripotency while simultaneously exhibiting lineage-bias. Using a MIXL1 reporter, we explore mesoderm lineage-bias within the human pluripotent stem cell compartment. We identify a substate, which at the single cell level c...

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Detalles Bibliográficos
Autores principales:	Stavish, Dylan, Böiers, Charlotta, Price, Christopher, Frith, Thomas J. R., Halliwell, Jason, Saldaña-Guerrero, Ingrid, Wray, Jason, Brown, John, Carr, Jonathon, James, Chela, Barbaric, Ivana, Andrews, Peter W., Enver, Tariq
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536399/ https://www.ncbi.nlm.nih.gov/pubmed/33020476 http://dx.doi.org/10.1038/s41467-020-18727-8

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