Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression

Despite a deeper molecular understanding, human glioblastoma remains one of the most treatment refractory and fatal cancers. It is known that the presence of macrophages and microglia impact glioblastoma tumorigenesis and prevent durable response. Herein we identify the dual function cytokine IL-33...

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Detalles Bibliográficos
Autores principales: De Boeck, Astrid, Ahn, Bo Young, D’Mello, Charlotte, Lun, Xueqing, Menon, Shyam V., Alshehri, Mana M., Szulzewsky, Frank, Shen, Yaoqing, Khan, Lubaba, Dang, Ngoc Ha, Reichardt, Elliott, Goring, Kimberly-Ann, King, Jennifer, Grisdale, Cameron J., Grinshtein, Natalie, Hambardzumyan, Dolores, Reilly, Karlyne M., Blough, Michael D., Cairncross, J. Gregory, Yong, V. Wee, Marra, Marco A., Jones, Steven J. M., Kaplan, David R., McCoy, Kathy D., Holland, Eric C., Bose, Pinaki, Chan, Jennifer A., Robbins, Stephen M., Senger, Donna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536425/
https://www.ncbi.nlm.nih.gov/pubmed/33020472
http://dx.doi.org/10.1038/s41467-020-18569-4

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