Spred2-deficiency enhances the proliferation of lung epithelial cells and alleviates pulmonary fibrosis induced by bleomycin

The mitogen-activated protein kinase (MAPK) pathways are involved in many cellular processes, including the development of fibrosis. Here, we examined the role of Sprouty-related EVH-1-domain-containing protein (Spred) 2, a negative regulator of the MAPK-ERK pathway, in the development of bleomycin...

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Detalles Bibliográficos
Autores principales: Kawara, Akina, Mizuta, Ryo, Fujisawa, Masayoshi, Ito, Toshihiro, Li, Chunning, Nakamura, Kaoru, Sun, Cuiming, Kuwabara, Masaki, Kitabatake, Masahiro, Yoshimura, Teizo, Matsukawa, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536438/
https://www.ncbi.nlm.nih.gov/pubmed/33020583
http://dx.doi.org/10.1038/s41598-020-73752-3

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