A Cyclodextrin‐Stabilized Spermine‐Tagged Drug Triplex that Targets Theophylline to the Lungs Selectively in Respiratory Emergency

Ion‐pairing a lifesaving drug such as theophylline with a targeting moiety could have a significant impact on medical emergencies such as status asthmaticus or COVID‐19 induced pneumomediastinum. However, to achieve rapid drug targeting in vivo the ion‐pair must be protected against breakdown before...

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Detalles Bibliográficos
Autores principales: Sofian, Zarif M., Benaouda, Faiza, Wang, Julie Tzu‐Wen, Lu, Yuan, Barlow, David J., Royall, Paul G., Farag, Doaa B., Rahman, Khondaker Miraz, Al‐Jamal, Khuloud T., Forbes, Ben, Jones, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536984/
https://www.ncbi.nlm.nih.gov/pubmed/33043128
http://dx.doi.org/10.1002/adtp.202000153

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