Cargando…

Characteristics and short‐term obstetric outcomes in a case series of 67 women test‐positive for SARS‐CoV‐2 in Stockholm, Sweden

INTRODUCTION: The Stockholm region was the first area in Sweden to be hit by the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). The national guidelines on the care of women with a positive test for SARS‐CoV‐2 (detection with polymerase chain reaction [PCR]) recommen...

Descripción completa

Detalles Bibliográficos
Autores principales: Remaeus, Katarina, Savchenko, Julia, Brismar Wendel, Sophia, Brusell Gidlöf, Sebastian, Graner, Sophie, Jones, Elin, Molin, Johanna, Saltvedt, Sissel, Wallström, Tove, Pettersson, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537005/
https://www.ncbi.nlm.nih.gov/pubmed/32981033
http://dx.doi.org/10.1111/aogs.14006
_version_ 1783590636480364544
author Remaeus, Katarina
Savchenko, Julia
Brismar Wendel, Sophia
Brusell Gidlöf, Sebastian
Graner, Sophie
Jones, Elin
Molin, Johanna
Saltvedt, Sissel
Wallström, Tove
Pettersson, Karin
author_facet Remaeus, Katarina
Savchenko, Julia
Brismar Wendel, Sophia
Brusell Gidlöf, Sebastian
Graner, Sophie
Jones, Elin
Molin, Johanna
Saltvedt, Sissel
Wallström, Tove
Pettersson, Karin
author_sort Remaeus, Katarina
collection PubMed
description INTRODUCTION: The Stockholm region was the first area in Sweden to be hit by the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). The national guidelines on the care of women with a positive test for SARS‐CoV‐2 (detection with polymerase chain reaction [PCR]) recommend individualized antenatal care, mode of delivery based on obstetric considerations, and no routine separation of the mother and the newborn. Breastfeeding is encouraged, and although there is no specific recommendation regarding wearing a face mask to prevent viral transmission to the newborn while nursing, instructions are given to keep high hygiene standards. All studies based on cases tested on hospital admission will capture more women with pregnancy complications than in the general population. Our aim was to describe the clinical characteristics of SARS‐CoV‐2‐positive women and their neonates, and to report short‐term maternal and neonatal outcomes. MATERIAL AND METHODS: A retrospective case series with data from medical records including all test‐positive women (n = 67) who gave birth to 68 neonates from 19 March to 26 April 2020 in Stockholm, Sweden. Means, proportions and percentages were calculated for clinical characteristics and outcomes. RESULTS: The mean age was 32 years, 40% were nulliparous and 61% were overweight or obese. Further, 15% had diabetes and 21% a hypertensive disease. Seventy percent of the women had a vaginal birth. Preterm delivery occurred in 19% of the women. The preterm deliveries were mostly medically indicated, including two women who were delivered preterm due to severe coronavirus disease 19 (COVID‐19), corresponding to 15% of the preterm births. Four women (6%) were admitted to the intensive care unit postpartum but there were no maternal deaths. There were two perinatal deaths (one stillbirth and one neonatal death). Three neonates were PCR‐positive for SARS‐CoV‐2 after birth. CONCLUSIONS: In this case series of 67 women testing positive for SARS‐CoV‐2 with clinical presentations ranging from asymptomatic to manifest COVID‐19 disease, few women presented with severe COVID‐19 illness. The majority had a vaginal birth at term with a healthy neonate that was negative for SARS‐CoV‐2.
format Online
Article
Text
id pubmed-7537005
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-75370052020-10-07 Characteristics and short‐term obstetric outcomes in a case series of 67 women test‐positive for SARS‐CoV‐2 in Stockholm, Sweden Remaeus, Katarina Savchenko, Julia Brismar Wendel, Sophia Brusell Gidlöf, Sebastian Graner, Sophie Jones, Elin Molin, Johanna Saltvedt, Sissel Wallström, Tove Pettersson, Karin Acta Obstet Gynecol Scand Pregnancy INTRODUCTION: The Stockholm region was the first area in Sweden to be hit by the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). The national guidelines on the care of women with a positive test for SARS‐CoV‐2 (detection with polymerase chain reaction [PCR]) recommend individualized antenatal care, mode of delivery based on obstetric considerations, and no routine separation of the mother and the newborn. Breastfeeding is encouraged, and although there is no specific recommendation regarding wearing a face mask to prevent viral transmission to the newborn while nursing, instructions are given to keep high hygiene standards. All studies based on cases tested on hospital admission will capture more women with pregnancy complications than in the general population. Our aim was to describe the clinical characteristics of SARS‐CoV‐2‐positive women and their neonates, and to report short‐term maternal and neonatal outcomes. MATERIAL AND METHODS: A retrospective case series with data from medical records including all test‐positive women (n = 67) who gave birth to 68 neonates from 19 March to 26 April 2020 in Stockholm, Sweden. Means, proportions and percentages were calculated for clinical characteristics and outcomes. RESULTS: The mean age was 32 years, 40% were nulliparous and 61% were overweight or obese. Further, 15% had diabetes and 21% a hypertensive disease. Seventy percent of the women had a vaginal birth. Preterm delivery occurred in 19% of the women. The preterm deliveries were mostly medically indicated, including two women who were delivered preterm due to severe coronavirus disease 19 (COVID‐19), corresponding to 15% of the preterm births. Four women (6%) were admitted to the intensive care unit postpartum but there were no maternal deaths. There were two perinatal deaths (one stillbirth and one neonatal death). Three neonates were PCR‐positive for SARS‐CoV‐2 after birth. CONCLUSIONS: In this case series of 67 women testing positive for SARS‐CoV‐2 with clinical presentations ranging from asymptomatic to manifest COVID‐19 disease, few women presented with severe COVID‐19 illness. The majority had a vaginal birth at term with a healthy neonate that was negative for SARS‐CoV‐2. John Wiley and Sons Inc. 2020-11-05 2020-12 /pmc/articles/PMC7537005/ /pubmed/32981033 http://dx.doi.org/10.1111/aogs.14006 Text en © 2020 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Pregnancy
Remaeus, Katarina
Savchenko, Julia
Brismar Wendel, Sophia
Brusell Gidlöf, Sebastian
Graner, Sophie
Jones, Elin
Molin, Johanna
Saltvedt, Sissel
Wallström, Tove
Pettersson, Karin
Characteristics and short‐term obstetric outcomes in a case series of 67 women test‐positive for SARS‐CoV‐2 in Stockholm, Sweden
title Characteristics and short‐term obstetric outcomes in a case series of 67 women test‐positive for SARS‐CoV‐2 in Stockholm, Sweden
title_full Characteristics and short‐term obstetric outcomes in a case series of 67 women test‐positive for SARS‐CoV‐2 in Stockholm, Sweden
title_fullStr Characteristics and short‐term obstetric outcomes in a case series of 67 women test‐positive for SARS‐CoV‐2 in Stockholm, Sweden
title_full_unstemmed Characteristics and short‐term obstetric outcomes in a case series of 67 women test‐positive for SARS‐CoV‐2 in Stockholm, Sweden
title_short Characteristics and short‐term obstetric outcomes in a case series of 67 women test‐positive for SARS‐CoV‐2 in Stockholm, Sweden
title_sort characteristics and short‐term obstetric outcomes in a case series of 67 women test‐positive for sars‐cov‐2 in stockholm, sweden
topic Pregnancy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537005/
https://www.ncbi.nlm.nih.gov/pubmed/32981033
http://dx.doi.org/10.1111/aogs.14006
work_keys_str_mv AT remaeuskatarina characteristicsandshorttermobstetricoutcomesinacaseseriesof67womentestpositiveforsarscov2instockholmsweden
AT savchenkojulia characteristicsandshorttermobstetricoutcomesinacaseseriesof67womentestpositiveforsarscov2instockholmsweden
AT brismarwendelsophia characteristicsandshorttermobstetricoutcomesinacaseseriesof67womentestpositiveforsarscov2instockholmsweden
AT brusellgidlofsebastian characteristicsandshorttermobstetricoutcomesinacaseseriesof67womentestpositiveforsarscov2instockholmsweden
AT granersophie characteristicsandshorttermobstetricoutcomesinacaseseriesof67womentestpositiveforsarscov2instockholmsweden
AT joneselin characteristicsandshorttermobstetricoutcomesinacaseseriesof67womentestpositiveforsarscov2instockholmsweden
AT molinjohanna characteristicsandshorttermobstetricoutcomesinacaseseriesof67womentestpositiveforsarscov2instockholmsweden
AT saltvedtsissel characteristicsandshorttermobstetricoutcomesinacaseseriesof67womentestpositiveforsarscov2instockholmsweden
AT wallstromtove characteristicsandshorttermobstetricoutcomesinacaseseriesof67womentestpositiveforsarscov2instockholmsweden
AT petterssonkarin characteristicsandshorttermobstetricoutcomesinacaseseriesof67womentestpositiveforsarscov2instockholmsweden