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The prevalence of gastrointestinal symptoms among patients with COVID‐19 and the effect on the severity of the disease

BACKGROUND AND AIM: COVID‐19 is a new pandemic disease recognized by the World Health Organization. It mainly affects the respiratory system, but it can also affect other systems. The gastrointestinal system has been found to be affected in many patients. This study investigated the COVID‐19‐related...

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Autores principales: Sulaiman, Tharwat, Algharawi, Ali A, Idrees, Marwan, Alzaidy, Rafid H, Faris, Kawthar, Cullingford, Graham, Rasheed, Jawad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537315/
https://www.ncbi.nlm.nih.gov/pubmed/33043143
http://dx.doi.org/10.1002/jgh3.12415
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author Sulaiman, Tharwat
Algharawi, Ali A
Idrees, Marwan
Alzaidy, Rafid H
Faris, Kawthar
Cullingford, Graham
Rasheed, Jawad
author_facet Sulaiman, Tharwat
Algharawi, Ali A
Idrees, Marwan
Alzaidy, Rafid H
Faris, Kawthar
Cullingford, Graham
Rasheed, Jawad
author_sort Sulaiman, Tharwat
collection PubMed
description BACKGROUND AND AIM: COVID‐19 is a new pandemic disease recognized by the World Health Organization. It mainly affects the respiratory system, but it can also affect other systems. The gastrointestinal system has been found to be affected in many patients. This study investigated the COVID‐19‐related gastrointestinal manifestations and the effect of gastrointestinal involvement on the course and outcome of the disease. METHODS: This was a retrospective descriptive study conducted on 140 COVID‐19 polymerase chain reaction‐positive symptomatic individuals admitted to Al‐Shafa Hospital – Medical City Complex in Baghdad, Iraq during the period 2 March 2020 to 12 May 2020. Demographic data and clinical presentation and laboratory data were extracted from the case sheets of the patients and were also obtained from direct communication with the patients, their families, and medical staff. RESULTS: Gastrointestinal (GI) symptoms alone were detected in 23.6% of the patients; 44.3% of the patients presented with only respiratory symptoms, and 32.1% presented with both respiratory and GI symptoms. Patients with only GI symptoms had less severe disease compared with those who had both GI and respiratory symptoms, who had more severe disease with higher mortality. Overall mortality was 8.6%, with no mortality in the GI symptoms alone group. The highest severity and mortality were in patients with both GI and respiratory symptoms (48.39 and 13.33%, respectively). CONCLUSIONS: COVID‐19‐related gastrointestinal symptoms are common, and their presence alone carries a better prognosis, but their presence with respiratory symptoms is associated with higher morbidity and mortality.
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spelling pubmed-75373152020-10-07 The prevalence of gastrointestinal symptoms among patients with COVID‐19 and the effect on the severity of the disease Sulaiman, Tharwat Algharawi, Ali A Idrees, Marwan Alzaidy, Rafid H Faris, Kawthar Cullingford, Graham Rasheed, Jawad JGH Open Original Articles BACKGROUND AND AIM: COVID‐19 is a new pandemic disease recognized by the World Health Organization. It mainly affects the respiratory system, but it can also affect other systems. The gastrointestinal system has been found to be affected in many patients. This study investigated the COVID‐19‐related gastrointestinal manifestations and the effect of gastrointestinal involvement on the course and outcome of the disease. METHODS: This was a retrospective descriptive study conducted on 140 COVID‐19 polymerase chain reaction‐positive symptomatic individuals admitted to Al‐Shafa Hospital – Medical City Complex in Baghdad, Iraq during the period 2 March 2020 to 12 May 2020. Demographic data and clinical presentation and laboratory data were extracted from the case sheets of the patients and were also obtained from direct communication with the patients, their families, and medical staff. RESULTS: Gastrointestinal (GI) symptoms alone were detected in 23.6% of the patients; 44.3% of the patients presented with only respiratory symptoms, and 32.1% presented with both respiratory and GI symptoms. Patients with only GI symptoms had less severe disease compared with those who had both GI and respiratory symptoms, who had more severe disease with higher mortality. Overall mortality was 8.6%, with no mortality in the GI symptoms alone group. The highest severity and mortality were in patients with both GI and respiratory symptoms (48.39 and 13.33%, respectively). CONCLUSIONS: COVID‐19‐related gastrointestinal symptoms are common, and their presence alone carries a better prognosis, but their presence with respiratory symptoms is associated with higher morbidity and mortality. Wiley Publishing Asia Pty Ltd 2020-09-18 /pmc/articles/PMC7537315/ /pubmed/33043143 http://dx.doi.org/10.1002/jgh3.12415 Text en © 2020 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Sulaiman, Tharwat
Algharawi, Ali A
Idrees, Marwan
Alzaidy, Rafid H
Faris, Kawthar
Cullingford, Graham
Rasheed, Jawad
The prevalence of gastrointestinal symptoms among patients with COVID‐19 and the effect on the severity of the disease
title The prevalence of gastrointestinal symptoms among patients with COVID‐19 and the effect on the severity of the disease
title_full The prevalence of gastrointestinal symptoms among patients with COVID‐19 and the effect on the severity of the disease
title_fullStr The prevalence of gastrointestinal symptoms among patients with COVID‐19 and the effect on the severity of the disease
title_full_unstemmed The prevalence of gastrointestinal symptoms among patients with COVID‐19 and the effect on the severity of the disease
title_short The prevalence of gastrointestinal symptoms among patients with COVID‐19 and the effect on the severity of the disease
title_sort prevalence of gastrointestinal symptoms among patients with covid‐19 and the effect on the severity of the disease
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537315/
https://www.ncbi.nlm.nih.gov/pubmed/33043143
http://dx.doi.org/10.1002/jgh3.12415
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