Cargando…
The very low number of calcium-induced permeability transition pores in the single mitochondrion
Mitochondrial permeability transition (PT) is a phenomenon of stress-induced increase in nonspecific permeability of the mitochondrial inner membrane that leads to disruption of oxidative phosphorylation and cell death. Quantitative measurement of the membrane permeability increase during PT is crit...
Autores principales: | Neginskaya, Maria A., Strubbe, Jasiel O., Amodeo, Giuseppe F., West, Benjamin A., Yakar, Shoshana, Bazil, Jason N., Pavlov, Evgeny V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537349/ https://www.ncbi.nlm.nih.gov/pubmed/32810269 http://dx.doi.org/10.1085/jgp.202012631 |
Ejemplares similares
-
The mitochondrial permeability transition phenomenon elucidated by cryo-EM reveals the genuine impact of calcium overload on mitochondrial structure and function
por: Strubbe-Rivera, Jasiel O., et al.
Publicado: (2021) -
Calcium Overload and Mitochondrial Metabolism
por: Walkon, Lauren L., et al.
Publicado: (2022) -
Calcium phosphate precipitation inhibits mitochondrial energy metabolism
por: Malyala, Sathyavani, et al.
Publicado: (2019) -
ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore
por: Neginskaya, Maria A., et al.
Publicado: (2019) -
Modeling the Effects of Calcium Overload on Mitochondrial Ultrastructural Remodeling
por: Strubbe-Rivera, Jasiel O., et al.
Publicado: (2021)