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Deciphering and predicting CD4(+) T cell immunodominance of influenza virus hemagglutinin

The importance of CD4(+) T helper (Th) cells is well appreciated in view of their essential role in the elicitation of antibody and cytotoxic T cell responses. However, the mechanisms that determine the selection of immunodominant epitopes within complex protein antigens remain elusive. Here, we use...

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Detalles Bibliográficos
Autores principales:	Cassotta, Antonino, Paparoditis, Philipp, Geiger, Roger, Mettu, Ramgopal R., Landry, Samuel J., Donati, Alessia, Benevento, Marco, Foglierini, Mathilde, Lewis, David J.M., Lanzavecchia, Antonio, Sallusto, Federica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537397/ https://www.ncbi.nlm.nih.gov/pubmed/32644114 http://dx.doi.org/10.1084/jem.20200206

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