Cancer cell CCR2 orchestrates suppression of the adaptive immune response

C-C chemokine receptor type 2 (CCR2) is expressed on monocytes and facilitates their recruitment to tumors. Though breast cancer cells also express CCR2, its functions in these cells are unclear. We found that Ccr2 deletion in cancer cells led to reduced tumor growth and approximately twofold longer...

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Detalles Bibliográficos
Autores principales: Fein, Miriam R., He, Xue-Yan, Almeida, Ana S., Bružas, Emilis, Pommier, Arnaud, Yan, Ran, Eberhardt, Anaïs, Fearon, Douglas T., Van Aelst, Linda, Wilkinson, John Erby, dos Santos, Camila O., Egeblad, Mikala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537399/
https://www.ncbi.nlm.nih.gov/pubmed/32667673
http://dx.doi.org/10.1084/jem.20181551

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