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Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors

Peripheral sympathetic nervous system tumors are the most common extracranial solid tumors of childhood and include neuroblastoma, ganglioneuroblastoma, and ganglioneuroma. Surgery is the only effective therapy for ganglioneuroma, which may be challenging due to the location of the tumor and involve...

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Detalles Bibliográficos
Autores principales:	Tao, Ting, Shi, Hui, Wang, Meng, Perez-Atayde, Antonio R., London, Wendy B., Gutierrez, Alejandro, Lemos, Bernardo, Durbin, Adam D., Look, A. Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537400/ https://www.ncbi.nlm.nih.gov/pubmed/32728700 http://dx.doi.org/10.1084/jem.20191871

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