Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis

TNF plays a key role in immune-mediated inflammatory diseases including rheumatoid arthritis (RA) and spondyloarthritis (SpA). It remains incompletely understood how TNF can lead to different disease phenotypes such as destructive peripheral polysynovitis in RA versus axial and peripheral osteoproli...

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Detalles Bibliográficos
Autores principales: Kaaij, Merlijn H., van Tok, Melissa N., Blijdorp, Iris C., Ambarus, Carmen A., Stock, Michael, Pots, Désiree, Knaup, Véronique L., Armaka, Marietta, Christodoulou-Vafeiadou, Eleni, van Melsen, Tessa K., Masdar, Huriatul, Eskes, Harry J.P.P., Yeremenko, Nataliya G., Kollias, George, Schett, Georg, Tas, Sander W., van Duivenvoorde, Leonie M., Baeten, Dominique L.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537402/
https://www.ncbi.nlm.nih.gov/pubmed/32662821
http://dx.doi.org/10.1084/jem.20200288

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