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Incremental effect of non-invasive oscillating device on chest physiotherapy in critically ill children: a cross-over randomised trial
INTRODUCTION: Chest physiotherapy (CPT) and intrathoracic percussion ventilation have been recognised as to encourage dislodging the secretions; nonetheless, the tolerance to the procedure and its efficiency have not been proven to be sufficient. METHOD AND ANALYSES: This study aims to examine the t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537431/ https://www.ncbi.nlm.nih.gov/pubmed/33020101 http://dx.doi.org/10.1136/bmjopen-2020-038648 |
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author | Kawaguchi, Atsushi Bernier, Gabrielle Adler, Andy Emeriaud, Guillaume Jouvet, Philippe A |
author_facet | Kawaguchi, Atsushi Bernier, Gabrielle Adler, Andy Emeriaud, Guillaume Jouvet, Philippe A |
author_sort | Kawaguchi, Atsushi |
collection | PubMed |
description | INTRODUCTION: Chest physiotherapy (CPT) and intrathoracic percussion ventilation have been recognised as to encourage dislodging the secretions; nonetheless, the tolerance to the procedure and its efficiency have not been proven to be sufficient. METHOD AND ANALYSES: This study aims to examine the tolerance, feasibility and physiological effects in airway clearance by using a novel extrathoracic non-invasive oscillating transducer device (NIOD) in critically ill children. A two-stage cross-over randomised controlled study in a paediatric intensive care unit in a Canadian Academic Children’s Hospital will be applied. Children under 24 months old, for whom CPT is prescribed for airway clearance, will be included. The study consists of two stages; (1) Stage 1 ‘Frequency Level’: we will apply two different frequencies of the NIOD (40 Hz vs 60 Hz) for 12 min each, on each patient 3 hours apart, and (2) Stage 2 ‘NIOD versus CPT’: we will implement NIOD and CPT alternatingly for 3 hours apart. The order of the procedures will be randomly allocated for each case. We will compare the average Δchanges of tidal lung volume measured by a 3D imaging system and regional lung functions using electrical impedance tomography, between the two different frequencies and between the NIOD periods and the CPT periods. We will also examine tolerance by seeing COMFORT Scales and related complications during the procedures. We estimate necessary sample size as 6 for each arm (Total 12 cases) for stage 1 and 48 cases for Stage 2, with power of 0.8 and alpha of 0.05. ETHICS AND DISSEMINATION: This study has been approved by the Health Research Ethics Board of University of Montreal, Canada (REB number: 2020-2471). We will disseminate our findings through peer-reviewed publications and conference presentations in paediatric or/and critical care fields. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov Registry (NCT03821389). |
format | Online Article Text |
id | pubmed-7537431 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-75374312020-10-07 Incremental effect of non-invasive oscillating device on chest physiotherapy in critically ill children: a cross-over randomised trial Kawaguchi, Atsushi Bernier, Gabrielle Adler, Andy Emeriaud, Guillaume Jouvet, Philippe A BMJ Open Paediatrics INTRODUCTION: Chest physiotherapy (CPT) and intrathoracic percussion ventilation have been recognised as to encourage dislodging the secretions; nonetheless, the tolerance to the procedure and its efficiency have not been proven to be sufficient. METHOD AND ANALYSES: This study aims to examine the tolerance, feasibility and physiological effects in airway clearance by using a novel extrathoracic non-invasive oscillating transducer device (NIOD) in critically ill children. A two-stage cross-over randomised controlled study in a paediatric intensive care unit in a Canadian Academic Children’s Hospital will be applied. Children under 24 months old, for whom CPT is prescribed for airway clearance, will be included. The study consists of two stages; (1) Stage 1 ‘Frequency Level’: we will apply two different frequencies of the NIOD (40 Hz vs 60 Hz) for 12 min each, on each patient 3 hours apart, and (2) Stage 2 ‘NIOD versus CPT’: we will implement NIOD and CPT alternatingly for 3 hours apart. The order of the procedures will be randomly allocated for each case. We will compare the average Δchanges of tidal lung volume measured by a 3D imaging system and regional lung functions using electrical impedance tomography, between the two different frequencies and between the NIOD periods and the CPT periods. We will also examine tolerance by seeing COMFORT Scales and related complications during the procedures. We estimate necessary sample size as 6 for each arm (Total 12 cases) for stage 1 and 48 cases for Stage 2, with power of 0.8 and alpha of 0.05. ETHICS AND DISSEMINATION: This study has been approved by the Health Research Ethics Board of University of Montreal, Canada (REB number: 2020-2471). We will disseminate our findings through peer-reviewed publications and conference presentations in paediatric or/and critical care fields. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov Registry (NCT03821389). BMJ Publishing Group 2020-10-05 /pmc/articles/PMC7537431/ /pubmed/33020101 http://dx.doi.org/10.1136/bmjopen-2020-038648 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Paediatrics Kawaguchi, Atsushi Bernier, Gabrielle Adler, Andy Emeriaud, Guillaume Jouvet, Philippe A Incremental effect of non-invasive oscillating device on chest physiotherapy in critically ill children: a cross-over randomised trial |
title | Incremental effect of non-invasive oscillating device on chest physiotherapy in critically ill children: a cross-over randomised trial |
title_full | Incremental effect of non-invasive oscillating device on chest physiotherapy in critically ill children: a cross-over randomised trial |
title_fullStr | Incremental effect of non-invasive oscillating device on chest physiotherapy in critically ill children: a cross-over randomised trial |
title_full_unstemmed | Incremental effect of non-invasive oscillating device on chest physiotherapy in critically ill children: a cross-over randomised trial |
title_short | Incremental effect of non-invasive oscillating device on chest physiotherapy in critically ill children: a cross-over randomised trial |
title_sort | incremental effect of non-invasive oscillating device on chest physiotherapy in critically ill children: a cross-over randomised trial |
topic | Paediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537431/ https://www.ncbi.nlm.nih.gov/pubmed/33020101 http://dx.doi.org/10.1136/bmjopen-2020-038648 |
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