Effects of SARS-CoV-2 and its functional receptor ACE2 on the cardiovascular system

The clinical manifestations of COVID-19 are mainly respiratory symptoms, but some patients present with cardiovascular system disease such as palpitations and shortness of breath as the first or secondary symptoms. In this paper, we describe the characteristics of SARS-CoV‑2 and its functional recep...

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Detalles Bibliográficos
Autores principales: Li, Mingzhe, Chen, Siyang, Xiang, Xiaochen, Wang, Qiang, Liu, Xiaoliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2020
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537586/
https://www.ncbi.nlm.nih.gov/pubmed/33025029
http://dx.doi.org/10.1007/s00059-020-04989-x
Descripción
Sumario:The clinical manifestations of COVID-19 are mainly respiratory symptoms, but some patients present with cardiovascular system disease such as palpitations and shortness of breath as the first or secondary symptoms. In this paper, we describe the characteristics of SARS-CoV‑2 and its functional receptor angiotensin-converting enzyme 2 (ACE2). Furthermore, we explore the impact of virus-induced myocardial damage, decreased ACE2 activity, immune imbalance, hypoxemia, and heart damage caused by antiviral drugs.

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