Effects of SARS-CoV-2 and its functional receptor ACE2 on the cardiovascular system

The clinical manifestations of COVID-19 are mainly respiratory symptoms, but some patients present with cardiovascular system disease such as palpitations and shortness of breath as the first or secondary symptoms. In this paper, we describe the characteristics of SARS-CoV‑2 and its functional recep...

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Detalles Bibliográficos
Autores principales: Li, Mingzhe, Chen, Siyang, Xiang, Xiaochen, Wang, Qiang, Liu, Xiaoliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2020
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537586/
https://www.ncbi.nlm.nih.gov/pubmed/33025029
http://dx.doi.org/10.1007/s00059-020-04989-x
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author Li, Mingzhe
Chen, Siyang
Xiang, Xiaochen
Wang, Qiang
Liu, Xiaoliu
author_facet Li, Mingzhe
Chen, Siyang
Xiang, Xiaochen
Wang, Qiang
Liu, Xiaoliu
author_sort Li, Mingzhe
collection PubMed
description The clinical manifestations of COVID-19 are mainly respiratory symptoms, but some patients present with cardiovascular system disease such as palpitations and shortness of breath as the first or secondary symptoms. In this paper, we describe the characteristics of SARS-CoV‑2 and its functional receptor angiotensin-converting enzyme 2 (ACE2). Furthermore, we explore the impact of virus-induced myocardial damage, decreased ACE2 activity, immune imbalance, hypoxemia, and heart damage caused by antiviral drugs.
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spelling pubmed-75375862020-10-07 Effects of SARS-CoV-2 and its functional receptor ACE2 on the cardiovascular system Li, Mingzhe Chen, Siyang Xiang, Xiaochen Wang, Qiang Liu, Xiaoliu Herz Review Articles The clinical manifestations of COVID-19 are mainly respiratory symptoms, but some patients present with cardiovascular system disease such as palpitations and shortness of breath as the first or secondary symptoms. In this paper, we describe the characteristics of SARS-CoV‑2 and its functional receptor angiotensin-converting enzyme 2 (ACE2). Furthermore, we explore the impact of virus-induced myocardial damage, decreased ACE2 activity, immune imbalance, hypoxemia, and heart damage caused by antiviral drugs. Springer Medizin 2020-10-06 2020 /pmc/articles/PMC7537586/ /pubmed/33025029 http://dx.doi.org/10.1007/s00059-020-04989-x Text en © Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Articles
Li, Mingzhe
Chen, Siyang
Xiang, Xiaochen
Wang, Qiang
Liu, Xiaoliu
Effects of SARS-CoV-2 and its functional receptor ACE2 on the cardiovascular system
title Effects of SARS-CoV-2 and its functional receptor ACE2 on the cardiovascular system
title_full Effects of SARS-CoV-2 and its functional receptor ACE2 on the cardiovascular system
title_fullStr Effects of SARS-CoV-2 and its functional receptor ACE2 on the cardiovascular system
title_full_unstemmed Effects of SARS-CoV-2 and its functional receptor ACE2 on the cardiovascular system
title_short Effects of SARS-CoV-2 and its functional receptor ACE2 on the cardiovascular system
title_sort effects of sars-cov-2 and its functional receptor ace2 on the cardiovascular system
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537586/
https://www.ncbi.nlm.nih.gov/pubmed/33025029
http://dx.doi.org/10.1007/s00059-020-04989-x
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AT wangqiang effectsofsarscov2anditsfunctionalreceptorace2onthecardiovascularsystem
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