Does cystic fibrosis constitute an advantage in COVID-19 infection?

The Veneto region is one of the most affected Italian regions by COVID-19. Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), may constitute a risk factor in COVID-19. Moreover, respiratory viruses were generally associated with severe pulmonary impairment in cystic fibrosi...

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Autores principales: Bezzerri, Valentino, Lucca, Francesca, Volpi, Sonia, Cipolli, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537774/
https://www.ncbi.nlm.nih.gov/pubmed/33023602
http://dx.doi.org/10.1186/s13052-020-00909-1
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author Bezzerri, Valentino
Lucca, Francesca
Volpi, Sonia
Cipolli, Marco
author_facet Bezzerri, Valentino
Lucca, Francesca
Volpi, Sonia
Cipolli, Marco
author_sort Bezzerri, Valentino
collection PubMed
description The Veneto region is one of the most affected Italian regions by COVID-19. Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), may constitute a risk factor in COVID-19. Moreover, respiratory viruses were generally associated with severe pulmonary impairment in cystic fibrosis (CF). We would have therefore expected numerous cases of severe COVID-19 among the CF population. Surprisingly, we found that CF patients were significantly protected against infection by SARS-CoV-2. We discussed this aspect formulating some reasonable theories.
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spelling pubmed-75377742020-10-07 Does cystic fibrosis constitute an advantage in COVID-19 infection? Bezzerri, Valentino Lucca, Francesca Volpi, Sonia Cipolli, Marco Ital J Pediatr Letter to the Editor The Veneto region is one of the most affected Italian regions by COVID-19. Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), may constitute a risk factor in COVID-19. Moreover, respiratory viruses were generally associated with severe pulmonary impairment in cystic fibrosis (CF). We would have therefore expected numerous cases of severe COVID-19 among the CF population. Surprisingly, we found that CF patients were significantly protected against infection by SARS-CoV-2. We discussed this aspect formulating some reasonable theories. BioMed Central 2020-10-06 /pmc/articles/PMC7537774/ /pubmed/33023602 http://dx.doi.org/10.1186/s13052-020-00909-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Letter to the Editor
Bezzerri, Valentino
Lucca, Francesca
Volpi, Sonia
Cipolli, Marco
Does cystic fibrosis constitute an advantage in COVID-19 infection?
title Does cystic fibrosis constitute an advantage in COVID-19 infection?
title_full Does cystic fibrosis constitute an advantage in COVID-19 infection?
title_fullStr Does cystic fibrosis constitute an advantage in COVID-19 infection?
title_full_unstemmed Does cystic fibrosis constitute an advantage in COVID-19 infection?
title_short Does cystic fibrosis constitute an advantage in COVID-19 infection?
title_sort does cystic fibrosis constitute an advantage in covid-19 infection?
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537774/
https://www.ncbi.nlm.nih.gov/pubmed/33023602
http://dx.doi.org/10.1186/s13052-020-00909-1
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