Cargando…

Mineral oil: safety and use as placebo in REDUCE-IT and other clinical studies

Mineral oil is often used as a clinical trial placebo. Pharmaceutical-grade mineral oil consists of a mixture of saturated hydrocarbons, with a purity and chemical structure that differs substantially from food-grade or technical-/industrial-grade mineral oils. Interest in mineral oil was piqued by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Olshansky, Brian, Chung, Mina K, Budoff, Matthew J, Philip, Sephy, Jiao, Lixia, Doyle, Jr., Ralph T, Copland, Christina, Giaquinto, Alex, Juliano, Rebecca A, Bhatt, Deepak L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537802/ https://www.ncbi.nlm.nih.gov/pubmed/33061866 http://dx.doi.org/10.1093/eurheartj/suaa117

Ejemplares similares

Comparison of mineral oil and non-mineral oil placebo on coronary plaque progression by coronary computed tomography angiography
por: Lakshmanan, Suvasini, et al.
Publicado: (2020)

Icosapent Ethyl Effects on Fatty Acid Profiles in Statin-Treated Patients With High Triglycerides: The Randomized, Placebo-controlled ANCHOR Study
por: Ballantyne, Christie M., et al.
Publicado: (2019)

REDUCE-IT USA: Results From the 3146 Patients Randomized in the United States
por: Bhatt, Deepak L., et al.
Publicado: (2020)

REDUCE-IT INTERIM: accumulation of data across prespecified interim analyses to final results
por: Olshansky, Brian, et al.
Publicado: (2020)

Cardiovascular Benefits of Icosapent Ethyl in Patients With and Without Atrial Fibrillation in REDUCE‐IT
por: Olshansky, Brian, et al.
Publicado: (2023)

Lipid Effects of Icosapent Ethyl in Women with Diabetes Mellitus and Persistent High Triglycerides on Statin Treatment: ANCHOR Trial Subanalysis
por: Brinton, Eliot A., et al.
Publicado: (2018)

EPA and DHA containing phospholipids have contrasting effects on membrane structure
por: Sherratt, Samuel C.R., et al.
Publicado: (2021)

Comparative Effects of Mineral Oil, Corn Oil, Eicosapentaenoic Acid, and Docosahexaenoic Acid in an In Vitro Atherosclerosis Model
por: Sherratt, Samuel C. R., et al.
Publicado: (2023)

Benefits of Icosapent Ethyl Across the Range of Kidney Function in Patients With Established Cardiovascular Disease or Diabetes: REDUCE-IT RENAL
por: Majithia, Arjun, et al.
Publicado: (2021)

Reduction in Revascularization With Icosapent Ethyl: Insights From REDUCE-IT Revascularization Analyses
por: Peterson, Benjamin E., et al.
Publicado: (2020)

Treatment With Icosapent Ethyl to Reduce Ischemic Events in Patients With Prior Percutaneous Coronary Intervention: Insights From REDUCE‐IT PCI
por: Peterson, Benjamin E., et al.
Publicado: (2022)

The potential population health impact of treating REDUCE-IT eligible US adults with Icosapent Ethyl
por: Derington, Catherine G., et al.
Publicado: (2022)

Effect of dietary pristane and other saturated mineral oils (MOSH) on autoimmune arthritis in rats
por: Andreassen, Monica, et al.
Publicado: (2017)

Mineral Oil in Peptic Ulcer
Publicado: (1917)

Mineral Oil as an Intestinal Lubricant
Publicado: (1916)

The Mineral Oil Hydrocarbon Paradox in Olive Pomace Oils
por: Gómez-Coca, Raquel B., et al.
Publicado: (2023)

Benefit of icosapent ethyl on coronary physiology assessed by computed tomography angiography fractional flow reserve: EVAPORATE-FFR(CT)
por: Rabbat, Mark G, et al.
Publicado: (2023)

Increased residual cardiovascular risk in U.S. veterans with moderately-elevated baseline triglycerides and well-controlled LDL-C levels on statins
por: Leatherman, Sarah, et al.
Publicado: (2022)

Potential effects of icosapent ethyl on cardiovascular outcomes in cigarette smokers: REDUCE-IT smoking
por: Miller, Michael, et al.
Publicado: (2022)

Comparison of Lactobacillus Sporogenes plus mineral oil and mineral oil alone in the treatment of childhood functional constipation
por: Saneian, Hossein, et al.
Publicado: (2013)

VCAM-1 Is Upregulated in Uranium Miners Compared to Other Miners
por: Ass’ad, Nour A., et al.
Publicado: (2021)

Impact of Icosapent Ethyl on Cardiovascular Risk Reduction in Patients With Heart Failure in REDUCE‐IT
por: Selvaraj, Senthil, et al.
Publicado: (2022)

Re: ‘Cardiovascular outcomes of ethyl eicosapentaenoic acid in diabetes mellitus: a meta-analysis’
por: Philip, Sephy
Publicado: (2023)

A Randomized, Placebo-Controlled Trial of Omega-3 Fatty Acids for Inhibition of Supraventricular Arrhythmias After Cardiac Surgery: The FISH Trial
por: Sandesara, Chirag M., et al.
Publicado: (2012)

Hepatic copper and other trace mineral concentrations in dogs with hepatocellular carcinoma
por: Harro, Cailin C., et al.
Publicado: (2019)

Synthetics, Mineral Oils, and Bio-Based Lubricants
por: Rudnick, Leslie
Publicado: (2013)

Mineral Composition of Elements in Walnuts and Walnut Oils
por: Juranović Cindrić, Iva, et al.
Publicado: (2018)

Analytical Methods for the Determination of Mineral Oil Saturated Hydrocarbons (MOSH) and Mineral Oil Aromatic Hydrocarbons (MOAH)—A Short Review
por: Weber, Sandra, et al.
Publicado: (2018)

Mineral weathering is linked to microbial priming in the critical zone
por: Fang, Qian, et al.
Publicado: (2023)

Heartburn relief with bicarbonate-rich mineral water: results of the randomised, placebo-controlled phase-III trial STOMACH STILL
por: Labenz, Joachim, et al.
Publicado: (2023)

Coronary Artery Calcium Screening: Does it Perform Better than Other Cardiovascular Risk Stratification Tools?
por: Zeb, Irfan, et al.
Publicado: (2015)

Placebo and other psychological interactions in headache treatment
por: Autret, A., et al.
Publicado: (2012)

Rosa × alba: source of essential minerals and volatile oils
por: Hosni, Karim
Publicado: (2011)

Mineral Oil Aspiration Related Juvenile Idiopathic Arthritis
por: Nelson, Andrew D., et al.
Publicado: (2015)

Recovery of Mineral Oil from Underground Electrical Cables
por: Caimi, Stefano, et al.
Publicado: (2019)

Update of the risk assessment of mineral oil hydrocarbons in food
por: Schrenk, Dieter, et al.
Publicado: (2023)

Offline Solid-Phase Extraction and Separation of Mineral Oil Saturated Hydrocarbons and Mineral Oil Aromatic Hydrocarbons in Edible Oils, and Analysis via GC with a Flame Ionization Detector
por: Ruiz, José Luis Hidalgo, et al.
Publicado: (2021)

Oil-Soluble Exogenous Catalysts and Reservoir Minerals Synergistically Catalyze the Aquathermolysis of Heavy Oil
por: Li, Yongfei, et al.
Publicado: (2023)

Evaluation of mineral oil saturated hydrocarbons (MOSH) and mineral oil aromatic hydrocarbons (MOAH) in pure mineral hydrocarbon-based cosmetics and cosmetic raw materials using (1)H NMR spectroscopy
por: Lachenmeier, Dirk W., et al.
Publicado: (2017)

Role of Omega-3 Fatty Acids in Cardiovascular Disease: the Debate Continues
por: Sherratt, Samuel C. R., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_s66h7i9uhs3bha8rt4oc55e5pu