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Circulating α4β7(+) Memory T Cells in Pediatric IBD Patients Express a Polyclonal T Cell Receptor Repertoire

BACKGROUND: The integrin α4β7 is highly expressed on activated T cells and is thought to direct homing of lymphocytes to the intestine. Since ulcerative colitis (UC) and Crohn’s disease (CD) are characterized by mucosal oligoclonal T cells’ expansion, we aimed to assess whether similar repertoire fe...

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Detalles Bibliográficos
Autores principales:	Gamliel, Adir, Werner, Lael, Pinsker, Marina, Salamon, Naomi, Weiss, Batia, Shouval, Dror S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537844/ https://www.ncbi.nlm.nih.gov/pubmed/33061522 http://dx.doi.org/10.2147/CEG.S271565

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