Rare Case of Docetaxel-Induced Myositis Detected on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Patient with Carcinoma Breast

We report an extremely rare case of acute inflammatory myopathy during combination chemotherapy with docetaxel and transtuzumab for metastatic breast carcinoma in a 44-year-old female patient. Despite the significant response in the follow-up fluorodeoxyglucose (FDG) positron emission tomography/com...

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Autores principales: Parida, Girish Kumar, Upadhyay, Amitabh, Mitra, Sujata, Suman, Akchata, Muthu, Gopal Sonai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537934/
https://www.ncbi.nlm.nih.gov/pubmed/33082686
http://dx.doi.org/10.4103/ijnm.IJNM_25_20
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author Parida, Girish Kumar
Upadhyay, Amitabh
Mitra, Sujata
Suman, Akchata
Muthu, Gopal Sonai
author_facet Parida, Girish Kumar
Upadhyay, Amitabh
Mitra, Sujata
Suman, Akchata
Muthu, Gopal Sonai
author_sort Parida, Girish Kumar
collection PubMed
description We report an extremely rare case of acute inflammatory myopathy during combination chemotherapy with docetaxel and transtuzumab for metastatic breast carcinoma in a 44-year-old female patient. Despite the significant response in the follow-up fluorodeoxyglucose (FDG) positron emission tomography/computed tomography, of the underlying malignancy to the chemotherapeutic regimen, there was diffusely increased FDG uptake in the upper and lower limb muscles with associated painful, proximal muscle weakness. These symptoms regressed after the discontinuation of docetaxel and the administration of corticosteroids, suggesting it to be the drug-induced myositis.
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spelling pubmed-75379342020-10-19 Rare Case of Docetaxel-Induced Myositis Detected on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Patient with Carcinoma Breast Parida, Girish Kumar Upadhyay, Amitabh Mitra, Sujata Suman, Akchata Muthu, Gopal Sonai Indian J Nucl Med Interesting Image We report an extremely rare case of acute inflammatory myopathy during combination chemotherapy with docetaxel and transtuzumab for metastatic breast carcinoma in a 44-year-old female patient. Despite the significant response in the follow-up fluorodeoxyglucose (FDG) positron emission tomography/computed tomography, of the underlying malignancy to the chemotherapeutic regimen, there was diffusely increased FDG uptake in the upper and lower limb muscles with associated painful, proximal muscle weakness. These symptoms regressed after the discontinuation of docetaxel and the administration of corticosteroids, suggesting it to be the drug-induced myositis. Wolters Kluwer - Medknow 2020 2020-07-01 /pmc/articles/PMC7537934/ /pubmed/33082686 http://dx.doi.org/10.4103/ijnm.IJNM_25_20 Text en Copyright: © 2020 Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Interesting Image
Parida, Girish Kumar
Upadhyay, Amitabh
Mitra, Sujata
Suman, Akchata
Muthu, Gopal Sonai
Rare Case of Docetaxel-Induced Myositis Detected on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Patient with Carcinoma Breast
title Rare Case of Docetaxel-Induced Myositis Detected on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Patient with Carcinoma Breast
title_full Rare Case of Docetaxel-Induced Myositis Detected on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Patient with Carcinoma Breast
title_fullStr Rare Case of Docetaxel-Induced Myositis Detected on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Patient with Carcinoma Breast
title_full_unstemmed Rare Case of Docetaxel-Induced Myositis Detected on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Patient with Carcinoma Breast
title_short Rare Case of Docetaxel-Induced Myositis Detected on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Patient with Carcinoma Breast
title_sort rare case of docetaxel-induced myositis detected on fluorodeoxyglucose positron emission tomography/computed tomography in a patient with carcinoma breast
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537934/
https://www.ncbi.nlm.nih.gov/pubmed/33082686
http://dx.doi.org/10.4103/ijnm.IJNM_25_20
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