Spinal Tuberculosis Mimicking as Prostate Cancer Metastases in Ga-68 Prostate-specific Membrane Antigen Positron-emission Tomography/Computed Tomography

Prostate-specific membrane antigen (PSMA) is a type II transmembrane glycoprotein which is overexpressed in prostate cancer. However, the widespread use of PSMA positron-emission tomography (PET) scan revealed various nonprostatic PSMA-avid diseases. Here we present a report of a known case of carci...

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Autores principales: Gupta, Nitin, Elumalai, Ram Kumar, Verma, Ritu, Belho, Ethel Shangne, Dhawan, Shashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537936/
https://www.ncbi.nlm.nih.gov/pubmed/33082696
http://dx.doi.org/10.4103/ijnm.IJNM_56_20
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author Gupta, Nitin
Elumalai, Ram Kumar
Verma, Ritu
Belho, Ethel Shangne
Dhawan, Shashi
author_facet Gupta, Nitin
Elumalai, Ram Kumar
Verma, Ritu
Belho, Ethel Shangne
Dhawan, Shashi
author_sort Gupta, Nitin
collection PubMed
description Prostate-specific membrane antigen (PSMA) is a type II transmembrane glycoprotein which is overexpressed in prostate cancer. However, the widespread use of PSMA positron-emission tomography (PET) scan revealed various nonprostatic PSMA-avid diseases. Here we present a report of a known case of carcinoma prostate, post orchidectomy, radiotherapy, on hormonal therapy with complain of back pain, referred for Ga68 PSMA PET/CT scan. The scan revealed PSMA-avid lesion of contiguous D6 and D7 vertebrae with associated soft-tissue component. The biopsy of the lesion was suggestive of tuberculosis.
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spelling pubmed-75379362020-10-19 Spinal Tuberculosis Mimicking as Prostate Cancer Metastases in Ga-68 Prostate-specific Membrane Antigen Positron-emission Tomography/Computed Tomography Gupta, Nitin Elumalai, Ram Kumar Verma, Ritu Belho, Ethel Shangne Dhawan, Shashi Indian J Nucl Med Interesting Image Prostate-specific membrane antigen (PSMA) is a type II transmembrane glycoprotein which is overexpressed in prostate cancer. However, the widespread use of PSMA positron-emission tomography (PET) scan revealed various nonprostatic PSMA-avid diseases. Here we present a report of a known case of carcinoma prostate, post orchidectomy, radiotherapy, on hormonal therapy with complain of back pain, referred for Ga68 PSMA PET/CT scan. The scan revealed PSMA-avid lesion of contiguous D6 and D7 vertebrae with associated soft-tissue component. The biopsy of the lesion was suggestive of tuberculosis. Wolters Kluwer - Medknow 2020 2020-07-01 /pmc/articles/PMC7537936/ /pubmed/33082696 http://dx.doi.org/10.4103/ijnm.IJNM_56_20 Text en Copyright: © 2020 Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Interesting Image
Gupta, Nitin
Elumalai, Ram Kumar
Verma, Ritu
Belho, Ethel Shangne
Dhawan, Shashi
Spinal Tuberculosis Mimicking as Prostate Cancer Metastases in Ga-68 Prostate-specific Membrane Antigen Positron-emission Tomography/Computed Tomography
title Spinal Tuberculosis Mimicking as Prostate Cancer Metastases in Ga-68 Prostate-specific Membrane Antigen Positron-emission Tomography/Computed Tomography
title_full Spinal Tuberculosis Mimicking as Prostate Cancer Metastases in Ga-68 Prostate-specific Membrane Antigen Positron-emission Tomography/Computed Tomography
title_fullStr Spinal Tuberculosis Mimicking as Prostate Cancer Metastases in Ga-68 Prostate-specific Membrane Antigen Positron-emission Tomography/Computed Tomography
title_full_unstemmed Spinal Tuberculosis Mimicking as Prostate Cancer Metastases in Ga-68 Prostate-specific Membrane Antigen Positron-emission Tomography/Computed Tomography
title_short Spinal Tuberculosis Mimicking as Prostate Cancer Metastases in Ga-68 Prostate-specific Membrane Antigen Positron-emission Tomography/Computed Tomography
title_sort spinal tuberculosis mimicking as prostate cancer metastases in ga-68 prostate-specific membrane antigen positron-emission tomography/computed tomography
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537936/
https://www.ncbi.nlm.nih.gov/pubmed/33082696
http://dx.doi.org/10.4103/ijnm.IJNM_56_20
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