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Primary non-adherence to inhaled medications measured with e-prescription data from Poland
BACKGROUND: Treatment adherence greatly influences the clinical outcomes in various fields of medicine, including management of asthma and COPD. With the recent implementation of a nationwide e-Health solutions in Poland, new and unique opportunities for studying primary non-adherence in asthma and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538175/ https://www.ncbi.nlm.nih.gov/pubmed/33033615 http://dx.doi.org/10.1186/s13601-020-00346-7 |
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author | Kardas, Grzegorz Panek, Michał Kuna, Piotr Kardas, Przemysław |
author_facet | Kardas, Grzegorz Panek, Michał Kuna, Piotr Kardas, Przemysław |
author_sort | Kardas, Grzegorz |
collection | PubMed |
description | BACKGROUND: Treatment adherence greatly influences the clinical outcomes in various fields of medicine, including management of asthma and COPD. With the recent implementation of a nationwide e-Health solutions in Poland, new and unique opportunities for studying primary non-adherence in asthma and COPD emerged. The aim was to study primary non-adherence to inhaled medications available in Poland indicated in asthma and/or COPD and analyse the impact of patients’ demographics and inhalers’ characteristics (dry powder inhalers (DPIs) vs metered dose inhalers (MDIs) and presence of a dosage counter) on primary non-adherence. METHODS: A retrospective analysis of all e-prescriptions issued in Poland in 2018 (n = 119,880) from the national e-prescription pilot framework. RESULTS: Primary non-adherence for inhalable medications reached 15.3%. It significantly differed among age groups—the lowest (10.8%) was in 75 + years-old patients, highest (18%) in 65–74 years-old patients. No gender differences in primary non-adherence were found. The highest non-adherence was observed for ICS + LABA combinations (18.86%). A significant difference was found between MDI and DPI inhalers and between inhalers with/without a dosage counter. CONCLUSIONS: Out of e-prescriptions for inhaled medications issued in 2018 in Poland, 15.3% were not redeemed. The degree of primary non-adherence was influenced by age, but not gender. Significant differences between MDIs and DPIs and between inhalers with/without a dosage counter were observed. |
format | Online Article Text |
id | pubmed-7538175 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-75381752020-10-07 Primary non-adherence to inhaled medications measured with e-prescription data from Poland Kardas, Grzegorz Panek, Michał Kuna, Piotr Kardas, Przemysław Clin Transl Allergy Research BACKGROUND: Treatment adherence greatly influences the clinical outcomes in various fields of medicine, including management of asthma and COPD. With the recent implementation of a nationwide e-Health solutions in Poland, new and unique opportunities for studying primary non-adherence in asthma and COPD emerged. The aim was to study primary non-adherence to inhaled medications available in Poland indicated in asthma and/or COPD and analyse the impact of patients’ demographics and inhalers’ characteristics (dry powder inhalers (DPIs) vs metered dose inhalers (MDIs) and presence of a dosage counter) on primary non-adherence. METHODS: A retrospective analysis of all e-prescriptions issued in Poland in 2018 (n = 119,880) from the national e-prescription pilot framework. RESULTS: Primary non-adherence for inhalable medications reached 15.3%. It significantly differed among age groups—the lowest (10.8%) was in 75 + years-old patients, highest (18%) in 65–74 years-old patients. No gender differences in primary non-adherence were found. The highest non-adherence was observed for ICS + LABA combinations (18.86%). A significant difference was found between MDI and DPI inhalers and between inhalers with/without a dosage counter. CONCLUSIONS: Out of e-prescriptions for inhaled medications issued in 2018 in Poland, 15.3% were not redeemed. The degree of primary non-adherence was influenced by age, but not gender. Significant differences between MDIs and DPIs and between inhalers with/without a dosage counter were observed. BioMed Central 2020-10-07 /pmc/articles/PMC7538175/ /pubmed/33033615 http://dx.doi.org/10.1186/s13601-020-00346-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Kardas, Grzegorz Panek, Michał Kuna, Piotr Kardas, Przemysław Primary non-adherence to inhaled medications measured with e-prescription data from Poland |
title | Primary non-adherence to inhaled medications measured with e-prescription data from Poland |
title_full | Primary non-adherence to inhaled medications measured with e-prescription data from Poland |
title_fullStr | Primary non-adherence to inhaled medications measured with e-prescription data from Poland |
title_full_unstemmed | Primary non-adherence to inhaled medications measured with e-prescription data from Poland |
title_short | Primary non-adherence to inhaled medications measured with e-prescription data from Poland |
title_sort | primary non-adherence to inhaled medications measured with e-prescription data from poland |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538175/ https://www.ncbi.nlm.nih.gov/pubmed/33033615 http://dx.doi.org/10.1186/s13601-020-00346-7 |
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