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Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex

Recognition of a start codon by the initiator aminoacyl-tRNA determines the reading frame of messenger RNA (mRNA) translation by the ribosome. In eukaryotes, the GTPase eIF5B collaborates in the correct positioning of the initiator Met-tRNA(i)(Met) on the ribosome in the later stages of translation...

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Detalles Bibliográficos
Autores principales:	Wang, Jinfan, Wang, Jing, Shin, Byung-Sik, Kim, Joo-Ran, Dever, Thomas E., Puglisi, Joseph D., Fernández, Israel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538418/ https://www.ncbi.nlm.nih.gov/pubmed/33024099 http://dx.doi.org/10.1038/s41467-020-18829-3

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