Effects on cardiac function, remodeling and inflammation following myocardial ischemia–reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice

Many novel therapies to treat myocardial infarction (MI), yielding promising results in animal models, nowadays failed in clinical trials for several reasons. The most used animal MI model is based on permanent ligation of the left anterior descending (LAD) coronary artery in healthy mice resulting...

Descripción completa

Detalles Bibliográficos
Autores principales: Pluijmert, Niek J., Bart, Cindy I., Bax, Wilhelmina H., Quax, Paul H. A., Atsma, Douwe E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538581/
https://www.ncbi.nlm.nih.gov/pubmed/33024178
http://dx.doi.org/10.1038/s41598-020-73608-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538581/
https://www.ncbi.nlm.nih.gov/pubmed/33024178
http://dx.doi.org/10.1038/s41598-020-73608-w

Ejemplares similares