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MicroRNA-223 decreases cell proliferation, migration, invasion, and enhances cell apoptosis in childhood acute lymphoblastic leukemia via targeting Forkhead box O 1

Objective: Acute lymphoblastic leukemia (ALL) is a frequent malignancy in childhood. The present study was aimed to investigate the effect of miR-223 in ALL and its underlying molecular mechanisms. Methods: The mRNA expression of miR-223 and FOXO1 was detected by qRT-RCR in ALL children. The correla...

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Detalles Bibliográficos
Autores principales: Li, Chunyu, Zhao, Tana, Nie, Lei, Zou, Yanhong, Zhang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538682/
https://www.ncbi.nlm.nih.gov/pubmed/32964916
http://dx.doi.org/10.1042/BSR20200485