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Diagnostic Test Criteria for HLA Genotyping to Prevent Drug Hypersensitivity Reactions: A Systematic Review of Actionable HLA Recommendations in CPIC and DPWG Guidelines

INTRODUCTION: Certain HLA variants are associated with an increased risk of hypersensitivity reactions to specific drugs. Both the Clinical Pharmacogenetics Implementation Consortium (CPIC) and the Dutch Pharmacogenetics Working Group (DPWG) have issued actionable HLA gene – drug interaction guideli...

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Detalles Bibliográficos
Autores principales:	Manson, Lisanne E. N., Swen, Jesse J., Guchelaar, Henk-Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538700/ https://www.ncbi.nlm.nih.gov/pubmed/33071783 http://dx.doi.org/10.3389/fphar.2020.567048

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