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Protective CD8(+) T-cell response against Hantaan virus infection induced by immunization with designed linear multi-epitope peptides in HLA-A2.1/K(b) transgenic mice

BACKGROUND: An effective vaccine that prevents disease caused by hantaviruses is a global public health priority, but up to now, no vaccine has been approved for worldwide use. Therefore, novel vaccines with high prophylaxis efficacy are urgently needed. METHODS: Herein, we designed and synthesized...

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Detalles Bibliográficos
Autores principales:	Ma, Ying, Tang, Kang, Zhang, Yusi, Zhang, Chunmei, Cheng, Linfeng, Zhang, Fanglin, Zhuang, Ran, Jin, Boquan, Zhang, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538842/ https://www.ncbi.nlm.nih.gov/pubmed/33028368 http://dx.doi.org/10.1186/s12985-020-01421-y

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