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Cell Development Deficiency and Gene Expression Dysregulation of Trisomy 21 Retina Revealed by Single-Nucleus RNA Sequencing

Retina is a crucial tissue for capturing and processing light stimulus. It is critical to describe the characteristics of retina at the single-cell level for understanding its biological functions. A variety of abnormalities in terms of morphology and function are present in the trisomy 21 (T21) ret...

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Detalles Bibliográficos
Autores principales: Hu, Fang-Yuan, Gao, Feng-Juan, Xu, Ping, Zhang, Sheng-Hai, Wu, Ji-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538860/
https://www.ncbi.nlm.nih.gov/pubmed/33072724
http://dx.doi.org/10.3389/fbioe.2020.564057