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RNA oxidation in chromatin modification and DNA-damage response following exposure to formaldehyde

Formaldehyde is an environmental and occupational chemical carcinogen implicated in the damage of proteins and nucleic acids. However, whether formaldehyde provokes modifications of RNAs such as 8-oxo-7,8-dihydroguanine (8-oxoG) and the role that these modifications play on conferring long-term adve...

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Detalles Bibliográficos
Autores principales: Gonzalez-Rivera, Juan C., Sherman, Mark W., Wang, Dongyu S., Chuvalo-Abraham, Jamie C. L., Hildebrandt Ruiz, Lea, Contreras, Lydia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538935/
https://www.ncbi.nlm.nih.gov/pubmed/33024153
http://dx.doi.org/10.1038/s41598-020-73376-7