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Using epidemic simulators for monitoring an ongoing epidemic
Prediction of infection trends, estimating the efficacy of contact tracing, testing or impact of influx of infected are of vital importance for administration during an ongoing epidemic. Most effective methods currently are empirical in nature and their relation to parameters of interest to administ...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538994/ https://www.ncbi.nlm.nih.gov/pubmed/33024160 http://dx.doi.org/10.1038/s41598-020-73308-5 |
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author | Raghavan, Mohan Sridharan, Kousik Sarathy Mandayam Rangayyan, Yashaswini |
author_facet | Raghavan, Mohan Sridharan, Kousik Sarathy Mandayam Rangayyan, Yashaswini |
author_sort | Raghavan, Mohan |
collection | PubMed |
description | Prediction of infection trends, estimating the efficacy of contact tracing, testing or impact of influx of infected are of vital importance for administration during an ongoing epidemic. Most effective methods currently are empirical in nature and their relation to parameters of interest to administrators are not evident. We thus propose a modified SEIRD model that is capable of modeling effect of interventions and inward migrations on the progress of an epidemic. The tunable parameters of this model bear relevance to monitoring of an epidemic. This model was used to show that some of the commonly seen features of cumulative infections in real data can be explained by piecewise constant changes in interventions and population influx. We also show that the data of cumulative infections from twelve Indian states between mid March and mid April 2020 can be generated from the model by applying interventions according to a set of heuristic rules. Prediction for the next ten days based on this model, reproduced real data very well. In addition, our model also reproduced the time series of recoveries and deaths. Our work constitutes an important first step towards an effective dashboard for the monitoring of epidemic by the administration, especially in an Indian context. |
format | Online Article Text |
id | pubmed-7538994 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-75389942020-10-08 Using epidemic simulators for monitoring an ongoing epidemic Raghavan, Mohan Sridharan, Kousik Sarathy Mandayam Rangayyan, Yashaswini Sci Rep Article Prediction of infection trends, estimating the efficacy of contact tracing, testing or impact of influx of infected are of vital importance for administration during an ongoing epidemic. Most effective methods currently are empirical in nature and their relation to parameters of interest to administrators are not evident. We thus propose a modified SEIRD model that is capable of modeling effect of interventions and inward migrations on the progress of an epidemic. The tunable parameters of this model bear relevance to monitoring of an epidemic. This model was used to show that some of the commonly seen features of cumulative infections in real data can be explained by piecewise constant changes in interventions and population influx. We also show that the data of cumulative infections from twelve Indian states between mid March and mid April 2020 can be generated from the model by applying interventions according to a set of heuristic rules. Prediction for the next ten days based on this model, reproduced real data very well. In addition, our model also reproduced the time series of recoveries and deaths. Our work constitutes an important first step towards an effective dashboard for the monitoring of epidemic by the administration, especially in an Indian context. Nature Publishing Group UK 2020-10-06 /pmc/articles/PMC7538994/ /pubmed/33024160 http://dx.doi.org/10.1038/s41598-020-73308-5 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Raghavan, Mohan Sridharan, Kousik Sarathy Mandayam Rangayyan, Yashaswini Using epidemic simulators for monitoring an ongoing epidemic |
title | Using epidemic simulators for monitoring an ongoing epidemic |
title_full | Using epidemic simulators for monitoring an ongoing epidemic |
title_fullStr | Using epidemic simulators for monitoring an ongoing epidemic |
title_full_unstemmed | Using epidemic simulators for monitoring an ongoing epidemic |
title_short | Using epidemic simulators for monitoring an ongoing epidemic |
title_sort | using epidemic simulators for monitoring an ongoing epidemic |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538994/ https://www.ncbi.nlm.nih.gov/pubmed/33024160 http://dx.doi.org/10.1038/s41598-020-73308-5 |
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