Frequency of the TP53 R337H variant in sporadic breast cancer and its impact on genomic instability

The R337H is a TP53 germline pathogenic variant that has been associated with several types of cancers, including breast cancer. Our main objective was to determine the frequency of the R337H variant in sporadic breast cancer patients from Paraná state, South Brazil, its association with prognosis a...

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Detalles Bibliográficos
Autores principales: Mathias, Carolina, Bortoletto, Stéfanne, Centa, Ariana, Komechen, Heloisa, Lima, Rubens S., Fonseca, Aline S., Sebastião, Ana Paula, Urban, Cícero A., Soares, Emerson W. S., Prando, Carolina, Figueiredo, Bonald C., Cavalli, Iglenir J., Cavalli, Luciane R., Ribeiro, Enilze M. F. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539008/
https://www.ncbi.nlm.nih.gov/pubmed/33024147
http://dx.doi.org/10.1038/s41598-020-73282-y

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