Anethole Dithiolethione Increases Glutathione in Kidney by Inhibiting γ-Glutamyltranspeptidase: Biochemical Interpretation and Pharmacological Consequences

AIMS: Anethole dithiolethione (ADT) is a marketed drug to treat xerostomia. Its mechanism of action is still unknown, but several preclinical studies indicate that it is able to increase intracellular glutathione (GSH) and protect against oxidative stress. Here, we investigated the molecular mechani...

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Detalles Bibliográficos
Autores principales: Giustarini, Daniela, Galvagni, Federico, Dalle-Donne, Isabella, Milzani, Aldo, Lucattelli, Monica, De Cunto, Giovanna, Bartolini, Desirée, Galli, Francesco, Santucci, Annalisa, Rossi, Ranieri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539083/
https://www.ncbi.nlm.nih.gov/pubmed/33062138
http://dx.doi.org/10.1155/2020/3562972

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