Oncogenic driver mutations predict outcome in a cohort of head and neck squamous cell carcinoma (HNSCC) patients within a clinical trial

234 diagnostic formalin-fixed paraffin-embedded (FFPE) blocks from homogeneously treated patients with locally advanced head and neck squamous cell carcinoma (HNSCC) within a multicentre phase III clinical trial were characterised. The mutational spectrum was examined by next generation sequencing i...

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Detalles Bibliográficos
Autores principales: Fernández-Mateos, Javier, Pérez-García, Jéssica, Seijas-Tamayo, Raquel, Mesía, Ricard, Rubió-Casadevall, Jordi, García-Girón, Carlos, Iglesias, Lara, Carral Maseda, Alberto, Adansa Klain, Juan Carlos, Taberna, Miren, Vazquez, Silvia, Gómez, María Asunción, del Barco, Edel, Ocana, Alberto, González-Sarmiento, Rogelio, Cruz-Hernández, Juan Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539152/
https://www.ncbi.nlm.nih.gov/pubmed/33024167
http://dx.doi.org/10.1038/s41598-020-72927-2

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