SETD8(C302R) Mutation Revealed from Myofibroblastoma‐Discordant Monozygotic Twins Leads to p53/p21 Deficit and WEE1 Inhibitor Sensitivity

High‐throughput gene sequencing has identified various genetic variants as the culprits for some common hereditary cancers. However, the heritability of a substantial proportion of cancers remains unexplained, which may result from rare deleterious mutations hidden in a myriad of nonsense genetic va...

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Detalles Bibliográficos
Autores principales: Li, Miao, Wang, Hongwu, Liao, Hongwei, Shen, Jiaxin, Wu, Yinfang, Wu, Yanping, Weng, Qingyu, Zhu, Chen, Geng, Xinwei, Lan, Fen, Xia, Yang, Zhang, Bin, Zou, Hang, Zhang, Nan, Zhou, Yunzhi, Chen, Zhihua, Shen, Huahao, Ying, Songmin, Li, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539211/
https://www.ncbi.nlm.nih.gov/pubmed/33042742
http://dx.doi.org/10.1002/advs.202001041

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