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A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures

BACKGROUND: We report our experience of treating anastomotic strictures using a novel type of fully covered metal stent (FCSEMS). This stent, known as the Kaffes Stent, is short-length with an antimigration waist and is easily removable due to long retrieval wires deployed within the duodenum. METHO...

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Detalles Bibliográficos
Autores principales: Warner, Ben, Harrison, Phillip, Farman, Muhammad, Devlin, John, Reffitt, David, El-Sherif, Yasser, Khorsandi, Shirin E., Prachalias, Andreas, Cerisuelo, Miriam Cortes, Menon, Krish, Jassem, Wayel, Srinivasan, Parthi, Vilca-Melendez, Hector, Heneghan, Michael, Heaton, Nigel, Joshi, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539398/
https://www.ncbi.nlm.nih.gov/pubmed/33028218
http://dx.doi.org/10.1186/s12876-020-01479-6
Descripción
Sumario:BACKGROUND: We report our experience of treating anastomotic strictures using a novel type of fully covered metal stent (FCSEMS). This stent, known as the Kaffes Stent, is short-length with an antimigration waist and is easily removable due to long retrieval wires deployed within the duodenum. METHODS: Sixty-two patients underwent ERCP and Kaffes stent insertion for post-transplant anastomotic strictures following confirmation of a stricture on MRCP. These patients were retrospectively analysed for immediate and long-term stricture resolution, improvement in symptoms and liver function tests (LFTs), stricture recurrence and complication rates. RESULTS: Of the 56 patients who had their stent removed at the time of analysis, 54 (96%) had immediate stricture resolution and 42 continued to have long-term resolution (mean follow-up period was 548 days). Of the 16 patients with symptoms of biliary obstruction, 13 had resolution of their symptoms. Overall, there was a significant improvement in LFTs after stent removal compared to before stent insertion. Complication rates were 15% with only one patient requiring biliary reconstruction. CONCLUSIONS: The Kaffes stent is effective and safe at resolving post liver transplant biliary anastomotic strictures.