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A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures

BACKGROUND: We report our experience of treating anastomotic strictures using a novel type of fully covered metal stent (FCSEMS). This stent, known as the Kaffes Stent, is short-length with an antimigration waist and is easily removable due to long retrieval wires deployed within the duodenum. METHO...

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Autores principales: Warner, Ben, Harrison, Phillip, Farman, Muhammad, Devlin, John, Reffitt, David, El-Sherif, Yasser, Khorsandi, Shirin E., Prachalias, Andreas, Cerisuelo, Miriam Cortes, Menon, Krish, Jassem, Wayel, Srinivasan, Parthi, Vilca-Melendez, Hector, Heneghan, Michael, Heaton, Nigel, Joshi, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539398/
https://www.ncbi.nlm.nih.gov/pubmed/33028218
http://dx.doi.org/10.1186/s12876-020-01479-6
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author Warner, Ben
Harrison, Phillip
Farman, Muhammad
Devlin, John
Reffitt, David
El-Sherif, Yasser
Khorsandi, Shirin E.
Prachalias, Andreas
Cerisuelo, Miriam Cortes
Menon, Krish
Jassem, Wayel
Srinivasan, Parthi
Vilca-Melendez, Hector
Heneghan, Michael
Heaton, Nigel
Joshi, Deepak
author_facet Warner, Ben
Harrison, Phillip
Farman, Muhammad
Devlin, John
Reffitt, David
El-Sherif, Yasser
Khorsandi, Shirin E.
Prachalias, Andreas
Cerisuelo, Miriam Cortes
Menon, Krish
Jassem, Wayel
Srinivasan, Parthi
Vilca-Melendez, Hector
Heneghan, Michael
Heaton, Nigel
Joshi, Deepak
author_sort Warner, Ben
collection PubMed
description BACKGROUND: We report our experience of treating anastomotic strictures using a novel type of fully covered metal stent (FCSEMS). This stent, known as the Kaffes Stent, is short-length with an antimigration waist and is easily removable due to long retrieval wires deployed within the duodenum. METHODS: Sixty-two patients underwent ERCP and Kaffes stent insertion for post-transplant anastomotic strictures following confirmation of a stricture on MRCP. These patients were retrospectively analysed for immediate and long-term stricture resolution, improvement in symptoms and liver function tests (LFTs), stricture recurrence and complication rates. RESULTS: Of the 56 patients who had their stent removed at the time of analysis, 54 (96%) had immediate stricture resolution and 42 continued to have long-term resolution (mean follow-up period was 548 days). Of the 16 patients with symptoms of biliary obstruction, 13 had resolution of their symptoms. Overall, there was a significant improvement in LFTs after stent removal compared to before stent insertion. Complication rates were 15% with only one patient requiring biliary reconstruction. CONCLUSIONS: The Kaffes stent is effective and safe at resolving post liver transplant biliary anastomotic strictures.
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spelling pubmed-75393982020-10-08 A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures Warner, Ben Harrison, Phillip Farman, Muhammad Devlin, John Reffitt, David El-Sherif, Yasser Khorsandi, Shirin E. Prachalias, Andreas Cerisuelo, Miriam Cortes Menon, Krish Jassem, Wayel Srinivasan, Parthi Vilca-Melendez, Hector Heneghan, Michael Heaton, Nigel Joshi, Deepak BMC Gastroenterol Research Article BACKGROUND: We report our experience of treating anastomotic strictures using a novel type of fully covered metal stent (FCSEMS). This stent, known as the Kaffes Stent, is short-length with an antimigration waist and is easily removable due to long retrieval wires deployed within the duodenum. METHODS: Sixty-two patients underwent ERCP and Kaffes stent insertion for post-transplant anastomotic strictures following confirmation of a stricture on MRCP. These patients were retrospectively analysed for immediate and long-term stricture resolution, improvement in symptoms and liver function tests (LFTs), stricture recurrence and complication rates. RESULTS: Of the 56 patients who had their stent removed at the time of analysis, 54 (96%) had immediate stricture resolution and 42 continued to have long-term resolution (mean follow-up period was 548 days). Of the 16 patients with symptoms of biliary obstruction, 13 had resolution of their symptoms. Overall, there was a significant improvement in LFTs after stent removal compared to before stent insertion. Complication rates were 15% with only one patient requiring biliary reconstruction. CONCLUSIONS: The Kaffes stent is effective and safe at resolving post liver transplant biliary anastomotic strictures. BioMed Central 2020-10-07 /pmc/articles/PMC7539398/ /pubmed/33028218 http://dx.doi.org/10.1186/s12876-020-01479-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Warner, Ben
Harrison, Phillip
Farman, Muhammad
Devlin, John
Reffitt, David
El-Sherif, Yasser
Khorsandi, Shirin E.
Prachalias, Andreas
Cerisuelo, Miriam Cortes
Menon, Krish
Jassem, Wayel
Srinivasan, Parthi
Vilca-Melendez, Hector
Heneghan, Michael
Heaton, Nigel
Joshi, Deepak
A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title_full A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title_fullStr A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title_full_unstemmed A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title_short A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title_sort unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539398/
https://www.ncbi.nlm.nih.gov/pubmed/33028218
http://dx.doi.org/10.1186/s12876-020-01479-6
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