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Allopregnanolone restores the tyrosine hydroxylase‐positive neurons and motor performance in a 6‐OHDA‐injected mouse model

AIMS: It has been reported that allopregnanolone (APα) promotes the neurogenesis of the neural progenitor cells (NPCs) in the subventricular zone (SVZ) and prevents the decrease of dopaminergic neurons in 6‐hydroxydopamine (6‐OHDA)‐treated mice by binding to γ‐aminobutyric acid A receptor (GABAAR) a...

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Detalles Bibliográficos
Autores principales: Chen, Zhi‐Chi, Wang, Tong‐Tong, Bian, Wei, Ye, Xin, Li, Meng‐Yi, Du, Juan‐Juan, Zhou, Peng, Cui, Huai‐Rui, Ding, Yu‐Qiang, Ren, Yan‐hua, Qi, Shuang‐Shuang, Yuan, Yuan‐Yuan, Liao, Min, Sun, Chen‐You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539840/
https://www.ncbi.nlm.nih.gov/pubmed/32602622
http://dx.doi.org/10.1111/cns.13432