Hypertonic saline mediates the NLRP3/IL‐1β signaling axis in microglia to alleviate ischemic blood‐brain barrier permeability by downregulating astrocyte‐derived VEGF in rats

INTRODUCTION: The aim of this study was to explore whether the antibrain edema of hypertonic saline (HS) is associated with alleviating ischemic blood‐brain barrier (BBB) permeability by downregulating astrocyte‐derived vascular endothelial growth factor (VEGF), which is mediated by microglia‐derive...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qiao‐sheng, Ding, Hong‐guang, Chen, Sheng‐long, Liu, Xin‐qiang, Deng, Yi‐yu, Jiang, Wen‐qiang, Li, Ya, Huang, Lin‐qiang, Han, Yong‐li, Wen, Miao‐yun, Wang, Mei‐qiu, Zeng, Hong‐ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539845/
https://www.ncbi.nlm.nih.gov/pubmed/32529750
http://dx.doi.org/10.1111/cns.13427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539845/
https://www.ncbi.nlm.nih.gov/pubmed/32529750
http://dx.doi.org/10.1111/cns.13427

Ejemplares similares