Mining the Antibody Repertoire for Solutions to SARS-CoV-2

In this issue of Cell Host & Microbe, Nielsen and colleagues sequence antibody repertoires of patients with severe COVID-19 to reveal potentially convergent features on the background of a larger, polyclonal response. Their findings suggest that, as databases improve, it may be possible to monit...

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Detalles Bibliográficos
Autores principales: Meng, Wenzhao, Rosenfeld, Aaron M., Luning Prak, Eline T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539899/
https://www.ncbi.nlm.nih.gov/pubmed/33031765
http://dx.doi.org/10.1016/j.chom.2020.09.010
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author Meng, Wenzhao
Rosenfeld, Aaron M.
Luning Prak, Eline T.
author_facet Meng, Wenzhao
Rosenfeld, Aaron M.
Luning Prak, Eline T.
author_sort Meng, Wenzhao
collection PubMed
description In this issue of Cell Host & Microbe, Nielsen and colleagues sequence antibody repertoires of patients with severe COVID-19 to reveal potentially convergent features on the background of a larger, polyclonal response. Their findings suggest that, as databases improve, it may be possible to monitor virus-specific B cells after infection or vaccination using antibody sequencing.
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spelling pubmed-75398992020-10-08 Mining the Antibody Repertoire for Solutions to SARS-CoV-2 Meng, Wenzhao Rosenfeld, Aaron M. Luning Prak, Eline T. Cell Host Microbe Preview In this issue of Cell Host & Microbe, Nielsen and colleagues sequence antibody repertoires of patients with severe COVID-19 to reveal potentially convergent features on the background of a larger, polyclonal response. Their findings suggest that, as databases improve, it may be possible to monitor virus-specific B cells after infection or vaccination using antibody sequencing. Elsevier Inc. 2020-10-07 2020-10-07 /pmc/articles/PMC7539899/ /pubmed/33031765 http://dx.doi.org/10.1016/j.chom.2020.09.010 Text en © 2020 Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Preview
Meng, Wenzhao
Rosenfeld, Aaron M.
Luning Prak, Eline T.
Mining the Antibody Repertoire for Solutions to SARS-CoV-2
title Mining the Antibody Repertoire for Solutions to SARS-CoV-2
title_full Mining the Antibody Repertoire for Solutions to SARS-CoV-2
title_fullStr Mining the Antibody Repertoire for Solutions to SARS-CoV-2
title_full_unstemmed Mining the Antibody Repertoire for Solutions to SARS-CoV-2
title_short Mining the Antibody Repertoire for Solutions to SARS-CoV-2
title_sort mining the antibody repertoire for solutions to sars-cov-2
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539899/
https://www.ncbi.nlm.nih.gov/pubmed/33031765
http://dx.doi.org/10.1016/j.chom.2020.09.010
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