Case fatality of COVID-19 in patients with neurodegenerative dementia

INTRODUCTION: The elderly population is the group most threatened by COVID-19, with the highest mortality rates. This study aims to analyse the case fatality of COVID-19 in a cohort of patients with degenerative dementia. METHODS: We conducted a descriptive case-control study of a sample of patients...

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Autores principales: Reyes-Bueno, J.A., Mena-Vázquez, N., Ojea-Ortega, T., Gonzalez-Sotomayor, M.M., Cabezudo-Garcia, P., Ciano-Petersen, N.L., Pons-Pons, G., Castro-Sánchez, M.V., Serrano-Castro, P.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedad Española de Neurología. Published by Elsevier España, S.L.U. 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539937/
https://www.ncbi.nlm.nih.gov/pubmed/32893069
http://dx.doi.org/10.1016/j.nrleng.2020.07.006
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author Reyes-Bueno, J.A.
Mena-Vázquez, N.
Ojea-Ortega, T.
Gonzalez-Sotomayor, M.M.
Cabezudo-Garcia, P.
Ciano-Petersen, N.L.
Pons-Pons, G.
Castro-Sánchez, M.V.
Serrano-Castro, P.J.
author_facet Reyes-Bueno, J.A.
Mena-Vázquez, N.
Ojea-Ortega, T.
Gonzalez-Sotomayor, M.M.
Cabezudo-Garcia, P.
Ciano-Petersen, N.L.
Pons-Pons, G.
Castro-Sánchez, M.V.
Serrano-Castro, P.J.
author_sort Reyes-Bueno, J.A.
collection PubMed
description INTRODUCTION: The elderly population is the group most threatened by COVID-19, with the highest mortality rates. This study aims to analyse the case fatality of COVID-19 in a cohort of patients with degenerative dementia. METHODS: We conducted a descriptive case-control study of a sample of patients diagnosed with primary neurodegenerative dementia. RESULTS: Twenty-four of the 88 patients with COVID-19 included in the study died: 10/23 (43.4%) patients diagnosed with dementia and 14/65 (21.5%) controls; this difference was statistically significant. DISCUSSION: Our results suggest that case fatality of COVID-19 is significantly higher among patients with primary degenerative dementia than in other patients with similar mean ages and comorbidities.
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spelling pubmed-75399372020-10-08 Case fatality of COVID-19 in patients with neurodegenerative dementia Reyes-Bueno, J.A. Mena-Vázquez, N. Ojea-Ortega, T. Gonzalez-Sotomayor, M.M. Cabezudo-Garcia, P. Ciano-Petersen, N.L. Pons-Pons, G. Castro-Sánchez, M.V. Serrano-Castro, P.J. Neurologia (Engl Ed) Original Article INTRODUCTION: The elderly population is the group most threatened by COVID-19, with the highest mortality rates. This study aims to analyse the case fatality of COVID-19 in a cohort of patients with degenerative dementia. METHODS: We conducted a descriptive case-control study of a sample of patients diagnosed with primary neurodegenerative dementia. RESULTS: Twenty-four of the 88 patients with COVID-19 included in the study died: 10/23 (43.4%) patients diagnosed with dementia and 14/65 (21.5%) controls; this difference was statistically significant. DISCUSSION: Our results suggest that case fatality of COVID-19 is significantly higher among patients with primary degenerative dementia than in other patients with similar mean ages and comorbidities. Sociedad Española de Neurología. Published by Elsevier España, S.L.U. 2020 2020-10-07 /pmc/articles/PMC7539937/ /pubmed/32893069 http://dx.doi.org/10.1016/j.nrleng.2020.07.006 Text en © 2020 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Article
Reyes-Bueno, J.A.
Mena-Vázquez, N.
Ojea-Ortega, T.
Gonzalez-Sotomayor, M.M.
Cabezudo-Garcia, P.
Ciano-Petersen, N.L.
Pons-Pons, G.
Castro-Sánchez, M.V.
Serrano-Castro, P.J.
Case fatality of COVID-19 in patients with neurodegenerative dementia
title Case fatality of COVID-19 in patients with neurodegenerative dementia
title_full Case fatality of COVID-19 in patients with neurodegenerative dementia
title_fullStr Case fatality of COVID-19 in patients with neurodegenerative dementia
title_full_unstemmed Case fatality of COVID-19 in patients with neurodegenerative dementia
title_short Case fatality of COVID-19 in patients with neurodegenerative dementia
title_sort case fatality of covid-19 in patients with neurodegenerative dementia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539937/
https://www.ncbi.nlm.nih.gov/pubmed/32893069
http://dx.doi.org/10.1016/j.nrleng.2020.07.006
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