The Plasmodium falciparum eIK1 kinase (PfeIK1) is central for melatonin synchronization in the human malaria parasite. Melatotosil blocks melatonin action on parasite cell cycle

Melatonin and its indoles derivatives are central in the synchronization of malaria parasites. In this research, we discovered that melatonin is unable to increase the parasitemia in the human malaria Plasmodium falciparum that lacks the kinase PfeIK1. The PfeIK1 knockout strain is a valuable tool i...

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Detalles Bibliográficos
Autores principales: Dias, Bárbara K.M., Nakabashi, Myna, Alves, Marina Rangel Rodrigues, Portella, Danielle Pagliaminuto, dos Santos, Benedito Matheus, Costa da Silva Almeida, Fahyme, Ribeiro, Ramira Yuri, Schuck, Desiree C., Jordão, Alessandro Kappel, Garcia, Celia R.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539967/
https://www.ncbi.nlm.nih.gov/pubmed/32702775
http://dx.doi.org/10.1111/jpi.12685

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