Sensitive and broadly applicable residual disease detection in acute myeloid leukemia using flow cytometry‐based leukemic cell enrichment followed by mutational profiling

Persistent measurable residual disease (MRD) is an increasingly important prognostic marker in acute myeloid leukemia (AML). Currently, MRD is determined by multi‐parameter flow cytometry (MFC) or PCR‐based methods detecting leukemia‐specific fusion transcripts and mutations. However, while MFC is h...

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Detalles Bibliográficos
Autores principales: Daga, Shruti, Rosenberger, Angelika, Kashofer, Karl, Heitzer, Ellen, Quehenberger, Franz, Halbwedl, Iris, Graf, Ricarda, Krisper, Nina, Prietl, Barbara, Höfler, Gerald, Reinisch, Andreas, Zebisch, Armin, Sill, Heinz, Wölfler, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540028/
https://www.ncbi.nlm.nih.gov/pubmed/32602117
http://dx.doi.org/10.1002/ajh.25918

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