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Aromatic (19)F–(13)C TROSY—[(19)F, (13)C]‐Pyrimidine Labeling for NMR Spectroscopy of RNA

We present the access to [5‐(19)F, 5‐(13)C]‐uridine and ‐cytidine phosphoramidites for the production of site‐specifically modified RNAs up to 65 nucleotides (nts). The amidites were used to introduce [5‐(19)F, 5‐(13)C]‐pyrimidine labels into five RNAs—the 30 nt human immunodeficiency virus trans ac...

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Detalles Bibliográficos
Autores principales:	Nußbaumer, Felix, Plangger, Raphael, Roeck, Manuel, Kreutz, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540360/ https://www.ncbi.nlm.nih.gov/pubmed/32558232 http://dx.doi.org/10.1002/anie.202006577

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