E35 ablates acute leukemia stem and progenitor cells in vitro and in vivo

Leukemia stem cells (LSCs) have critical functions in acute leukemia (AL) pathogenesis, participating in its initiation and relapse. Thus, identifying new molecules to eradicate LSCs represents a high priority for AL management. This work identified E35, a novel Emodin derivative, which strongly inh...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yingyu, Zheng, Jing, Gan, Donghui, Chen, Yanxin, Zhang, Na, Chen, Yuwen, Lin, Zhenxing, Wang, Wenfeng, Chen, Haijun, Lin, Donghong, Hu, Jianda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540425/
https://www.ncbi.nlm.nih.gov/pubmed/31960417
http://dx.doi.org/10.1002/jcp.29457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540425/
https://www.ncbi.nlm.nih.gov/pubmed/31960417
http://dx.doi.org/10.1002/jcp.29457

Ejemplares similares